ACS Journals Logo
Journal of Medicinal Chemistry logo

Volume 13
Main Index

Issue 1


Aroylpiperidines and pyrrolidines. New class of potent central nervous system depressants
Robert L. Duncan, Grover C. Helsley, William J. Welstead, John P. DaVanzo, William H. Funderburk, and Carl D. Lunsford
pp 1 - 6; DOI:
10.1021/jm00295a001
PDF
Azabicyclo chemistry. I. Synthesis of 1,5-methano-7-methoxy-2,3,4,5-tetrahydro-1H-2-benzazepines. B-norbenzomorphans
Arthur E. Jacobson and Michael Mokotoff
pp 7 - 9; DOI:
10.1021/jm00295a002
PDF
3'-Methyl, 8-methyl, and 8-phenyl derivatives of 5,9-dimethyl-6,7-benzomorphans
Albert Ziering, Nicholas Malatestinic, Thomas Williams, and Arnold Brossi
pp 9 - 13; DOI:
10.1021/jm00295a003
PDF
Thioxanthene psychopharmacological agents. I. 9-(3-Aminopropyl)thioxanthene-2-sulfonamides
James F. Muren and Barry M. Bloom
pp 14 - 16; DOI:
10.1021/jm00295a004
PDF
Thioxanthene psychopharmacological agents. II. 9-(3-aminopropylidene)-N,N-dimethylthioxanthene-2-sulfonamides
James F. Muren and Barry M. Bloom
pp 17 - 23; DOI:
10.1021/jm00295a005
PDF
4'-Fluoro-4-(1,4,5,6-tetrahydroazepino[4,5-b]indol-3(2H)-yl)butyrophenones
J. B. Hester, A. D. Rudzik, H. H. Keasling, and W. Veldkamp
pp 23 - 26; DOI:
10.1021/jm00295a006
PDF
Analogs of .alpha.-methylphenethylamine (amphetamine). I. Synthesis and pharmacological activity of some methoxy and/or methyl analogs
Beng-Thong Ho, William M. McIsaac, Rong An, L. Wayne Tansey, Kenneth E. Walker, Leo F. Englert, and Michael B. Noel
pp 26 - 30; DOI:
10.1021/jm00295a007
PDF
Pharmacologic and metabolic studies with deuterated zoxazolamine
Masato Tanabe, Josephine Tagg, Dennis Yasuda, Susanna E. LeValley, and Chozo Mitoma
pp 30 - 32; DOI:
10.1021/jm00295a008
PDF
2-(4-Imidazolyl)cyclopropylamine
Alfred Burger, Manuel Bernabe, and Paul Waddell Collins
pp 33 - 35; DOI:
10.1021/jm00295a009
PDF
Novel type of substituted piperazine with high antiserotonin potency
W. J. Van der Burg, I. L. Bonta, J. Delobelle, C. Ramon, and B. Vargaftig
pp 35 - 39; DOI:
10.1021/jm00295a010
PDF
Effect of eight prostaglandins on platelet aggregation
N. Chandra Sekhar
pp 39 - 44; DOI:
10.1021/jm00295a011
PDF
Inhibition of viral neuraminidase by 1-phenoxymethyl-3,4-dihydroisoquinolines. I. Steric effects
Michael S. Tute, Keith W. Brammer, Barry Kaye, and Reginald W. Broadbent
pp 44 - 48; DOI:
10.1021/jm00295a012
PDF
Inhibition of viral neuraminidase by 1-phenoxymethyl-3,4-dihydroisoquinolines. II. Hansch analysis
Michael S. Tute
pp 48 - 51; DOI:
10.1021/jm00295a013
PDF
Metabolic fate of phenyltrimethylsilane and phenyldimethylsilane
Ralph J. Fessenden and Ray A. Hartman
pp 52 - 54; DOI:
10.1021/jm00295a014
PDF
Antifertility agents. IV. 2,3-Diphenylbenzo- and 5,6-polymethylenebenzofurans, 1,2-diphenylnaphthofurans, and some related compounds
H. P. S. Chawla, P. K. Grover, Nitya Anand, V. P. Kamboj, and Amiya B. Kar
pp 54 - 59; DOI:
10.1021/jm00295a015
PDF
Synthesis and hypoglycemic activity of substituted alkyl- and alkoxyguanidines
Bernard J. Ludwig, David B. Reisner, Mervin Meyer, Leo S. Powell, Leon Simet, and Frank J. Stiefel
pp 60 - 63; DOI:
10.1021/jm00295a016
PDF
Fluorinated pyrimidines. XXXIII. Synthesis of methylated 5-fluoro-2'-deoxyuridine derivatives
Tasneem A. Khwaja and Charles Heidelberger
pp 64 - 69; DOI:
10.1021/jm00295a017
PDF
Fluorinated pyrimidines. XXXIV. Structure-activity studies of methylated 5-fluoro-2'-deoxyuridine derivatives
Raymond J. Kent, Tasneem A. Khwaja, and Charles Heidelberger
pp 70 - 73; DOI:
10.1021/jm00295a018
PDF
Synthesis and thiolytic cleavage of S-acyl derivatives of 5-mercaptouracil and 5-mercapto-2'-deoxyuridine
Michael P. Kotick, Thomas I. Kalman, and Thomas J. Bardos
pp 74 - 77; DOI:
10.1021/jm00295a019
PDF
Cofactor inhibition of thymidylate synthetase. Tetrahydrofolic acid analogs
Mathias P. Mertes and Ai Jeng Lin
pp 77 - 82; DOI:
10.1021/jm00295a020
PDF
Irreversible enzyme inhibitors. CLXVI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine with 6 substituents and some factors in their cell wall transport
Bernard Randall Baker and Nicolaas M. J. Vermeulen
pp 82 - 86; DOI:
10.1021/jm00295a021
PDF
Irreversible enzyme inhibitors. CLXVII. Thymidine phosphorylase. 10. On the nature and dimensions of the hydrophobic bonding region. A
Bernard Randall Baker and Stephen E. Hopkins
pp 87 - 89; DOI:
10.1021/jm00295a022
PDF
6-Fluorotetracyclines
Panayota Bitha, Joseph J. Hlavka, and James H. Boothe
pp 89 - 92; DOI:
10.1021/jm00295a023
PDF
Predictability of correlations between in vitro tetracycline potencies and substituent indices
Arthur Cammarata and Suh Jen Yau
pp 93 - 97; DOI:
10.1021/jm00295a024
PDF
Antiprotozoal quinones. II. Synthesis of 4-amino-1,2-naphthoquinones and related compounds as potential antimalarials
F. J. Bullock, J. F. Tweedie, D. D. McRitchie, and M. A. Tucker
pp 97 - 103; DOI:
10.1021/jm00295a025
PDF
Synthetic schistosomicides. XIV. 1,4-Naphthoquinone mono(O-acyloximes), 4-amino-1,2-naphthoquinones, 2-amino-3-chloro-1,4-naphthoquinones, and other naphthoquinones
Edward F. Elslager, Leslie M. Werbel, and Donald F. Worth
pp 104 - 109; DOI:
10.1021/jm00295a026
PDF
Novel anthelmintic agents. IV. Noncyclic amidines related to pyrantel
James W. McFarland and Harold L. Howes
pp 109 - 113; DOI:
10.1021/jm00295a027
PDF
Novel anthelmintic agents. V. Thiazoline and dihydrothiazine analogs of pyrantel
James W. McFarland, Harold L. Howes, L. H. Conover, J. E. Lynch, William C. Austin, and D. H. Morgan
pp 113 - 119; DOI:
10.1021/jm00295a028
PDF
Quinoxaline studies. XV. Potential antimalarials. (RS)-.alpha.-(dialkylaminomethyl)-2-quinoxalinemethanols
Henry R. Moreno and Harry Pershing Schultz
pp 119 - 121; DOI:
10.1021/jm00295a029
PDF
Anthelmintic quaternary salts. V. 2-(p-Dialkylaminophenyl)-1-methylquinolinium salts
G. Y. Paris, D. L. Garmaise, J. Komlossy, and R. C. McCrae
pp 122 - 124; DOI:
10.1021/jm00295a030
PDF
Synthesis of .gamma.-dimethylamino-.alpha.-phenylcycloaklyl propionates as potential analgetics
Mathias P. Mertes, Patrick E. Hanna, and Arthur A. Ramsey
pp 125 - 128; DOI:
10.1021/jm00295a031
PDF
Insect chemosterilants. VIII. Boron compounds
Joseph A. Settepani, Jerry B. Stokes, and Alexej B. Borkovec
pp 128 - 131; DOI:
10.1021/jm00295a032
PDF
Optical isomers of metaraminol. Synthesis and biological activity
Noel F. Albertson, F. C. McKay, H. E. Lape, J. O. Hoppe, W. H. Selberis, and A. Arnold
pp 132 - 134; DOI:
10.1021/jm00295a033
PDF
Amphetamine analogs. II. Methylated phenethylamines
Beng-Thong Ho, L. Wayne Tansey, Robert L. Balster, Rong An, William M. McIsaac, and Robert T. Harris
pp 134 - 135; DOI:
10.1021/jm00295a034
PDF
Substituted quinazolonephenoxyethylhydrazines as monoamine oxidase inhibitors
Surendra S. Parmar and Ramesh Chandra Arora
pp 135 - 136; DOI:
10.1021/jm00295a035
PDF
Antiinflammatory agents. I. 3-Benzoylfluoroalkanesulfonanilides
J. Kenneth Harrington, Jerry Earl Robertson, Donald C. Kvam, Robert R. Hamilton, Kelly T. McGurran, Ronald J. Trancik, Karl F. Swingle, George Gomer Innes Moore, and John F. Gerster
pp 137 - 137; DOI:
10.1021/jm00295a036
PDF
1,4-Bis(2-indol-3-ylethyl)piperidines
John L. Archibald, Thomas Baum, and Scott J. Childress
pp 138 - 140; DOI:
10.1021/jm00295a037
PDF
Derivatives of 9-thioxanthenecarbonitrile
James F. Muren
pp 140 - 141; DOI:
10.1021/jm00295a038
PDF
Synthesis and hypoglycemic activity of 2-(.omega.-substituted alkylamino)-2-imidazolines
D. B. Reisner, Bernard J. Ludwig, S. Gister, and K. Tomeczek
pp 142 - 143; DOI:
10.1021/jm00295a039
PDF
Potential antidiabetics. Benzimidazole-2-sulfonylglycamide derivatives
S. M. Deshpande, K. C. Datta, A. K. Sanyal, and M. K. Raina
pp 143 - 144; DOI:
10.1021/jm00295a040
PDF
Conformational aspects of ureas in the inhibition of the Hill reaction
Marvin R. Boots, Sharon G. Boots, and Donald E. Moreland
pp 144 - 144; DOI:
10.1021/jm00295a041
PDF
1,2,3,4,6,7,12,12a-Octahydro-2-phenylpyrazino[2',1':6,1]pyrido[3,4-b]indole
John W. Schulenberg and Donald F. Page
pp 145 - 145; DOI:
10.1021/jm00295a042
PDF
Electronic factors in drug-receptor interactions
Yvonne C. Martin
pp 145 - 147; DOI:
10.1021/jm00295a043
PDF
.beta.-Amino ketones as inhibitors of pyruvic acid oxidation
Rajendra S. Varma, Basheer Ali, Surendra S. Parmar, and W. Lewis Nobles
pp 147 - 148; DOI:
10.1021/jm00295a044
PDF
Synthesis of 6-trifluoromethyl-1,4-dihydrazinophthalazine
Bruno Cavalleri, Elvio Bellasio, and Anna Sardi
pp 148 - 149; DOI:
10.1021/jm00295a045
PDF
Synthesis of the .alpha. and .beta. anomers of 1-(2-deoxy-D-ribofuranosyl)-2-pyridone
Mathias P. Mertes
pp 149 - 151; DOI:
10.1021/jm00295a046
PDF
Fluorinated pyrimidines. XXXVI. Synthesis of some 2,4-substituted 5-trifluoromethylpyrimidines
Heino Diringer, Tasneem A. Khwaja, and Charles Heidelberger
pp 151 - 152; DOI:
10.1021/jm00295a047
PDF
Synthesis and activity of a new class of heterocyclic compounds against Entamoeba histolytica. 1,2,3,3a-Tetrahydro-1-alkylcyclopenta[de]quinolines
A. U. Dey and B. Pathak
pp 152 - 153; DOI:
10.1021/jm00295a048
PDF
Antimalarials. 4-Substituted 1H-pyrazolo[3,4-b]quinolines
Robert G. Stein, John H. Biel, and Tara Singh
pp 153 - 155; DOI:
10.1021/jm00295a049
PDF
Febrifugine antimalarial agents. I. Pyridine analogs of febrifugine
Morris Fishman and Philip A. Cruickshank
pp 155 - 156; DOI:
10.1021/jm00295a050
PDF
Synthesis and antimalarial activity of amodiaquine analogs
Ned D. Heindel and James Molnar
pp 156 - 157; DOI:
10.1021/jm00295a051
PDF
Arylglyoxal N,N-disubstituted hydrazones with antiviral and antifungal activity
Elena Massarani, Dante Nardi, R. Pozzi, and L. Degen
pp 157 - 159; DOI:
10.1021/jm00295a052
PDF
Synthesis and antimicrobial activity of some thenoyl amides
M. Likar, P. Schauer, M. Japelj, M. Globokar, M. Oklobdzija, A. Povse, and V. Sunjic
pp 159 - 161; DOI:
10.1021/jm00295a053
PDF
Synthesis of 5,8-quinazolinedione
Giorgio Malesani, Francesco Marcolin, and Giovanni Rodighiero
pp 161 - 162; DOI:
10.1021/jm00295a054
PDF
Terpene compounds as drugs. VII. Terpenylhydroxamic acids
Silvano Casadio, Antonio Mantegani, Amedeo Omodei Sale, and Germano Coppi
pp 162 - 164; DOI:
10.1021/jm00295a055
PDF
Nitrofuryl heterocycles. IX. Some derivatives and analogs of 6,7-dihydro-3-(5-nitro-2-furyl)-5H-imidazo[2,1-b]thiazolium chloride
Harry R. Snyder and Louis E. Benjamin
pp 164 - 165; DOI:
10.1021/jm00295a056
PDF
Diethylaminoethyl ethers of coumarins
Satyendra Kumar
pp 166 - 166; DOI:
10.1021/jm00295a057
PDF
Reaction of chloroquinolines with formamides
Ned D. Heindel and Peter D. Kennewell
pp 166 - 167; DOI:
10.1021/jm00295a058
PDF
Synthesis of 3-bromo- and 3-chloro-1-methyl-4-phenyl-4-propionoxypiperidines as potential analgetics
Philip M. Carabateas
pp 167 - 167; DOI:
10.1021/jm00295a059
PDF
The American Society for Pharmacology and Experimental Therapeutics. The First Sixty Years. 1908-1969
Alfred Burger
pp 168 - 168; DOI:
10.1021/jm00295a900
PDF
Solid Phase Peptide Synthesis
Keith O. Hodgson
pp 168 - 168; DOI:
10.1021/jm00295a901
PDF
Annual Reports in Medicinal Chemistry, 1968.
Alfred Burger
pp 168 - 168; DOI:
10.1021/jm00295a902
PDF

Issue 2


.beta.-Adrenergic blocking agents. VII. 2-(1,4-Benzodioxanyl) and 2-chromanyl analogs of pronethalol [2-isopropylamino-1-(2-naphthyl) ethanol]
Ralph Howe, Balbir S. Rao, and M. S. Chodnekar
pp 169 - 176; DOI:
10.1021/jm00296a001
PDF
Analogs of angiotensin II. I. Solid phase synthesis
N. C. Chaturvedi, Won Kil Park, R. R. Smeby, and F. M. Bumpus
pp 177 - 181; DOI:
10.1021/jm00296a002
PDF
Analogs of angiotensin II. II. Mechanism of receptor interaction
Philip A. Khairallah, A. Toth, and F. M. Bumpus
pp 181 - 184; DOI:
10.1021/jm00296a003
PDF
[2,4-Diisoleucine]-oxytocin. Analog of oxytocin with natriuretic and diuretic activities
Victor J. Hruby, Vincent Du Vigneaud, and Wah-Yip Chan
pp 185 - 187; DOI:
10.1021/jm00296a004
PDF
Pyridoxine chemistry. XXII. Selective modifications of the .alpha.4-position of pyridoxol. I. Extension and branching of the 4-side chain
Wsewolod Korytnyk and Burton Paul
pp 187 - 191; DOI:
10.1021/jm00296a005
PDF
Antidepressants. II. Bridged ring ether derivatives in the dibenzocycloheptene series
Marcia E. Christy, Carole C. Boland, June G. Williams, and Edward L. Engelhardt
pp 191 - 195; DOI:
10.1021/jm00296a006
PDF
Synthesis and activity of some 3-substituted 1,2,3,4-pseudooxatriazol-5-ones and their precursors and related compounds
T. L. Thomas, M. Fedorchuk, B. V. Shetty, and F. E. Anderson
pp 196 - 203; DOI:
10.1021/jm00296a007
PDF
Nonsteroidal antiinflammatory agents. I. 6-Substituted 2-naphthylacetic acids
Ian Thomas Harrison, Brian Lewis, Peter Nelson, Wendell Rooks, Adolph Roszkowski, Albert Tomolonis, and John H. Fried
pp 203 - 205; DOI:
10.1021/jm00296a008
PDF
Preparation and antiinflammatory activity of some 2-arylbenzo[b] thiophen-3(2H)-one 1,1-dioxides
Joseph G. Lombardino and Edward H. Wiseman
pp 206 - 210; DOI:
10.1021/jm00296a009
PDF
Synthesis and pharmacological properties of substituted cinnamohydroxamic acids
N. P. Buu-Hoi, Claude L. Gillet, Georges E. Lambelin, Jose L. Roba, and Jacques E. Thiriaux
pp 211 - 213; DOI:
10.1021/jm00296a010
PDF
Sulfur and selenium compounds related to acetylcholine and choline. X. Acetylthionocholine
Shih-Hsi Chu and Henry G. Mautner
pp 214 - 215; DOI:
10.1021/jm00296a011
PDF
In vitro inhibition of cholesterolgenesis by various thyroid hormone analogs
Cleamond D. Eskelson, Clarence R. Cazee, W. Anthony, Jack C. Towne, and Benedict R. Walske
pp 215 - 220; DOI:
10.1021/jm00296a012
PDF
Choline acetyltransferase inhibitors. Dimensional and substituent effects among styrylpyridine analogs
Chester J. Cavallito, H. S. Yun, T. Kaplan, John Crispin Smith, and Francis F. Foldes
pp 221 - 224; DOI:
10.1021/jm00296a013
PDF
Structure-activity relations. I. Series of antagonists of acetylcholine and histamine at the postganglionic receptors
Keith Bowden and Rodney Christopher Young
pp 225 - 230; DOI:
10.1021/jm00296a014
PDF
Antimalarials. 8-chloro-4-(2'-N,N-dibutylamino-1'-hydroxyethyl) benzo[h]-1,6-naphthyridine
Karl A. Roseman, Maribeth M. Gould, Warner M. Linfield, and Ben E. Edwards
pp 230 - 233; DOI:
10.1021/jm00296a015
PDF
Syntheses of phenanthrene amino alcohols as antimalarials
Leroy Krbechek, Richard R. Riter, Richard G. Wagner, and Clarence W. Huffman
pp 234 - 238; DOI:
10.1021/jm00296a016
PDF
Nitrones. II. .alpha.-(5-Nitro-2-furyl)-N-cycloalkyl- and -N-alkylnitrones
Hyun Koo Kim, Hesham K. Yaktin, and Ronald E. Bambury
pp 238 - 241; DOI:
10.1021/jm00296a017
PDF
N-sulfanilyl-l-alkylcytosines. New highly active class of "soluble," short-acting sulfanilamides
Leonard Doub, Uldis Krolls, J. M. Vandenbelt, and Myron W. Fisher
pp 242 - 246; DOI:
10.1021/jm00296a018
PDF
Preparation and antibacterial activity of some sulfanilamidodiazines bearing the N-alkylalkanesulfonamido group
William E. Kreighbaum, Frederick A. Grunwald, Edward F. Harrison, John A. LaBudde, and A. A. Larsen
pp 247 - 251; DOI:
10.1021/jm00296a019
PDF
Potential antiradiation agents. III. N-substituted aminoethane-thiosulfuric acids
Daniel L. Klayman, Marie M. Grenan, and David P. Jacobus
pp 251 - 254; DOI:
10.1021/jm00296a020
PDF
Antiviral agents. I. Bicyclo[2.2.2]octan- and -oct-2-enamines
Joel G. Whitney, W. A. Gregory, J. C. Kauer, J. R. Roland, Jack A. Snyder, R. E. Benson, and E. C. Hermann
pp 254 - 260; DOI:
10.1021/jm00296a021
PDF
Antiprotozoal quinones. III. Synthesis of 8-amino-5,6-quinolinediones, 8-amino-7-chloro-5,6-quinolinediones, and 8-amino-5,5,7-trichloro-6(5H)-quinolones as potential antimalarials
F. J. Bullock and J. F. Tweedie
pp 261 - 264; DOI:
10.1021/jm00296a022
PDF
Preparation and the results of antitumor screening of some substituted amino-, azido-, halogeno- and hydroxy-p-benzoquinones
Kwang-Yuen Zee-Cheng and Chia-Chung Cheng
pp 264 - 268; DOI:
10.1021/jm00296a023
PDF
Nucleosides. LXIV. Fluoro sugar analogs of arabinosyl- and xylosylcytosines
John Arthur Wright, Dan Patrick Wilson, and Jack J. Fox
pp 269 - 272; DOI:
10.1021/jm00296a024
PDF
Effect of some heterocyclic disulfides and thiones on the carbohydrate metabolism of Ehrlich ascites tumor
Davide R. Grassetti, John F. Murray, M. E. Brokke, and A. D. Gutman
pp 273 - 276; DOI:
10.1021/jm00296a025
PDF
Cofactor inhibitors of thymidylate synthetase. Piperidine and tetrahydroquinoline analogs of tetrahydrofolic acid
Mathias P. Mertes and Ai Jeng Lin
pp 276 - 279; DOI:
10.1021/jm00296a026
PDF
Irreversible enzyme inhibitors. CLXVIII. Irreversible inhibition of dihydrofolate reductase and cell wall transport by pyrimidines and dihydro-s-triazines with pyridinium side chains
Bernard Randall Baker, Nicolaas M. J. Vermeulen, and Adrian J. Ryan
pp 280 - 284; DOI:
10.1021/jm00296a027
PDF
Mixed bifunctionality. II. Relation of antitumor activity to structure in alkylating agents derived from polynuclear aromatic hydrocarbons
Richard M. Peck, Anna P. O'Connell, and Hugh J. Creech
pp 284 - 288; DOI:
10.1021/jm00296a028
PDF
Nitrofuryl heterocycles. X. Analogs of 6-(5-nitro-2-furyl)-as-triazine-3,5(2H,4H)-dione
Homer A. Burch
pp 288 - 291; DOI:
10.1021/jm00296a029
PDF
Nitrofuryl heterocycles. XI. 3-(5-Nitro-2-furyl)-.DELTA.2-1,2,4-triazolin-5-ones
Louis E. Benjamin, Homer A. Burch, and Richard Dobson
pp 291 - 292; DOI:
10.1021/jm00296a030
PDF
Synthesis of 1-phenyl-2-styryl-3,5-dioxopyrazolidines as antiinflammatory agents
Hisao Yamamoto and Shinichi Kaneko
pp 292 - 295; DOI:
10.1021/jm00296a031
PDF
2-Trifluoromethoxydibenz[b,e][1,4]diazepine and 2-trifluoromethoxydibenz[b,f][1,4]-oxazepine derivatives
Francis J. McEvoy, E. N. Greenblatt, A. C. Osterberg, and George Rodger Allen
pp 295 - 297; DOI:
10.1021/jm00296a032
PDF
.alpha.,.alpha.,.alpha.-Trifluorotoluic acid (5-nitrofurfurylidene)hydrazides
Dean E. Welch, Harry S. Nakaue, and Robert D. Vatne
pp 297 - 298; DOI:
10.1021/jm00296a033
PDF
Comparison of some stereochemical requirements of the acetyl-cholinesterase and muscarinic receptor areas
George H. Cocolas, Ellen Chenault Robinson, and William L. Dewey
pp 299 - 301; DOI:
10.1021/jm00296a034
PDF
Phosphorus-nitrogen compounds. XI. Phosphamidase studies. I. Unsubstituted amides
Lindley A. Cates
pp 301 - 302; DOI:
10.1021/jm00296a035
PDF
Synthesis of pentazocine
Noel F. Albertson and William F. Wetterau
pp 302 - 303; DOI:
10.1021/jm00296a036
PDF
Substituted benzamides. Analogs of .beta.-hydroxyethylcyclohexylamine with CNS [central nervous system] depressant and hypotensive activity
William D. Roll
pp 303 - 304; DOI:
10.1021/jm00296a037
PDF
Synthesis of some local anesthetics
Pramod K. Srivastava and P. N. Srivastava
pp 304 - 305; DOI:
10.1021/jm00296a038
PDF
Synthesis of compounds with potential central nervous system stimulant activity. II. 5-Spiro-substituted 2-amino-2-oxazolines
Michael R. Harnden and Ray R. Rasmussen
pp 305 - 308; DOI:
10.1021/jm00296a039
PDF
3-Substituted 1,2,3,4-tetrahydrocarbazoles
Leonard M. Rice and Kenneth Richard Scott
pp 308 - 311; DOI:
10.1021/jm00296a040
PDF
16-Oxygenated 17.alpha.-methyl-5.beta.-androstanes
Tadashi Watabe, Sachiko Yagishita, and Shoji Hara
pp 311 - 312; DOI:
10.1021/jm00296a041
PDF
Synthesis of 1-(3'-N,N-diethylaminopropyl)-2-alkylnaphth[1,2-d]-imidazole-4,5-diones
F. Ivy Carroll, J. T. Blackwell, and H. Wayne Miller
pp 312 - 314; DOI:
10.1021/jm00296a042
PDF
Analogs of steroid hormones. III. Benz[e]indene derivatives
Richard E. Juday, Bonnie Bukwa, Kent Kaiser, and Gordon Webb
pp 314 - 317; DOI:
10.1021/jm00296a043
PDF
Organic disulfides and related substances. XXVIII. Analogs of o-(2-protoaminoethyldithio)benzoate as antiradiation drugs
Lamar Field and Patton M. Giles
pp 317 - 319; DOI:
10.1021/jm00296a044
PDF
Effect of organic compounds on reproductive processes. VIII. Methanesulfonyloxyacetyl derivatives of diamines
Wilfred A. Skinner and J. G. Johansson
pp 319 - 320; DOI:
10.1021/jm00296a045
PDF
Cassaine analogs. VI. Resolution of (.dag.)-7-deoxy-16,17,18,20-tetranorcassaic acid and biological activity of derived esters
Robert LaGrone Clarke and Sol J. Daum
pp 320 - 322; DOI:
10.1021/jm00296a046
PDF
Preparation and fungistatic properties of thiocarbohydrazones
David M. Wiles and Tony Suprunchuk
pp 323 - 324; DOI:
10.1021/jm00296a047
PDF
Antiprotozoal 4-aryloxy-2-aminoquinolines and related compounds
Diether G. Markees, Virginia C. Dewey, and George W. Kidder
pp 324 - 326; DOI:
10.1021/jm00296a048
PDF
Antimalarials. 4,4'-Diaminodiphenyl sulfone-type compounds
Tara Singh, Robert George Stein, and John H. Biel
pp 326 - 327; DOI:
10.1021/jm00296a049
PDF
Synthetic trypanocides. I. Substituted 1,2,3,4-tetrahydrocarbazoles
Jorge G. Pecca and Sem M. Albonico
pp 327 - 328; DOI:
10.1021/jm00296a050
PDF
Derivatives of 2-hydroxy-p-phenetidine. I. Azomethines
Moses J. Namkung and T. Lloyd Fletcher
pp 329 - 329; DOI:
10.1021/jm00296a051
PDF
2,3-Dihydro-4(1H)-quinazolinone derivatives
Giuseppe Bonola and Enrico Sianesi
pp 329 - 332; DOI:
10.1021/jm00296a052
PDF
Hexachlorocyclopentadiene adducts of unsaturated amides
Robert R. Mod, Frank C. Magne, Evald L. Skau, and Gene Sumrell
pp 332 - 333; DOI:
10.1021/jm00296a053
PDF
4-Demethyltrichocereine
Sidney Teitel and Arnold Brossi
pp 333 - 333; DOI:
10.1021/jm00296a054
PDF
Quaternization products of S-(--)-nicotine
Charles H. Jarboe and Charlotte M. Schmidt
pp 333 - 334; DOI:
10.1021/jm00296a055
PDF
1-Arylsulfonylhydrazides. III. 4-Phenyl-1-arylsulfonylthiosemicarbazides and 2-arylsulfonylhydrazone-3-phenyl-4-thiazolines
Carlos Sunkel and Humberto Gomez
pp 334 - 335; DOI:
10.1021/jm00296a056
PDF
Aminopyrimidine steroid
David M. Piatak and Eliahu Caspi
pp 335 - 335; DOI:
10.1021/jm00296a057
PDF
Antituberculous Schiff bases
Jaysukhlal R. Merchant and D. S. Chothia
pp 335 - 336; DOI:
10.1021/jm00296a058
PDF
Principles of Drug Action. The Basis of Pharmacology
Avram Goldstein, Lewis Aronow, and Sumner M. Kalman
pp 337 - 337; DOI:
10.1021/jm00296a900
PDF
Circulatory Drugs. Pharmacological and Clinical Approach to the Detection and Evaluation of New Circulatory Drugs
A. Bertelli
pp 337 - 337; DOI:
10.1021/jm00296a901
PDF
Pharmaceutical Chemistry. Part II: Inorganic
M.L. Schroff
pp 337 - 337; DOI:
10.1021/jm00296a902
PDF
Atlas of Protein Sequence and Structure 1969
Alfred Burger
pp 337 - 337; DOI:
10.1021/jm00296a903
PDF
Isolation and Identification of Drugs in Pharmaceuticals. Body Fluids, and Post-mortem Material

pp 338 - 338; DOI:
10.1021/jm00296a905
PDF

Issue 3


Polypeptides. XLV. Structure-function studies in the .beta.-corticotropin series
Klaus Hofmann, Rudolf Andreatta, Hans Bohn, and Luis Moroder
pp 339 - 345; DOI:
10.1021/jm00297a001
PDF
Synthesis and pharmacological properties of 4-decarboxamido-8-arginine-vasopressin and its 1-deamino analog
Dieter Gillessen and Vincent Du Vigneaud
pp 346 - 349; DOI:
10.1021/jm00297a002
PDF
Synthesis of analogs of the C-terminal octapeptide of cholecystokinin-pancreozymin. Structure-activity relation
Josip Pluscec, John T. Sheehan, Emily F. Sabo, Nina Williams, Octavian Kocy, and Miguel A. Ondetti
pp 349 - 352; DOI:
10.1021/jm00297a003
PDF
Angiotensin II analogs. III. Synthesis and biological evaluation of some des-aspartyl-angiotensins
Eugene C. Jorgensen, Graham C. Windridge, and Thomas Choy Lee
pp 352 - 356; DOI:
10.1021/jm00297a004
PDF
Synthesis and positive inotropic effect of strophanthidol 3-bromoacetate-19-3H
Richard Edward Thomas, Barbara F. Roth-Schechter, and George T. Okita
pp 357 - 359; DOI:
10.1021/jm00297a005
PDF
Hypocholesteremic agents. I. Substituted stilbazoles and dihydrostilbazoles
Frank J. Villani, Claire A. Ellis, Robert F. Tavares, Merl Steinberg, and Sibylle Tolksdorf
pp 359 - 366; DOI:
10.1021/jm00297a006
PDF
Thyroxine analogs. XVIII. 3,5-Dialkyl-3'-halo-DL-thyronines and their 3'-methyl and 4'-amino analogs
Eugene C. Jorgensen and Jeremy Wright
pp 367 - 370; DOI:
10.1021/jm00297a007
PDF
Synthetic schistosomicides. XVI. 5-(Mono- and dialkylamino)-2-nitrosophenols, 2-amino-5-(dialkylamino)phenols, and related compounds
Edward F. Elslager and Donald F. Worth
pp 370 - 376; DOI:
10.1021/jm00297a008
PDF
N-substituted N'-hydroxythioureas
Gil Clifton, Sarah R. Bryant, and Charles G. Skinner
pp 377 - 379; DOI:
10.1021/jm00297a009
PDF
8-Hydroxyquinoline derivatives. Synthesis and biological evaluation of arylglyoxal N-7-amino-5-substituted 8-hydroxyquinoline hemiacetals and 5-phenylglyoxylidenamino-8-hydroxyquinolines
Elena Massarani, Dante Nardi, R. Pozzi, L. Degen, and Maria J. Magistretti
pp 380 - 383; DOI:
10.1021/jm00297a010
PDF
Potential antimalarials. IV. Quinoline-.alpha.,.alpha.-dialkylmethanols
Joel B. Wommack and Donald E. Pearson
pp 383 - 386; DOI:
10.1021/jm00297a011
PDF
Chemical conversion of desacetylcephalothin lactone into desacetylcephalothin. The final link in a total synthesis of cephalosporanic acid derivatives
Saul L. Neidleman, Samuel C. Pan, Jerold A. Last, and Joseph E. Dolfini
pp 386 - 388; DOI:
10.1021/jm00297a012
PDF
Transformations of 6-phenylacetamido- and 6-tritylaminopenicillanyl p-toluenesulfonate and p-nitrobenzenesulfonate
Malcolm Rice Bell, Stephen D. Clemans, and Rudolf Oesterlin
pp 389 - 394; DOI:
10.1021/jm00297a013
PDF
2-Tetrahydropyridylindoles as histamine and serotonin antagonists
Robert N. Schut, Frederick E. Ward, O. J. Lorenzetti, and Enrique Hong
pp 394 - 397; DOI:
10.1021/jm00297a014
PDF
.beta.-Adrenergic blocking agents. VIII. Reactions of .beta.-haloalkylamines related to pronethalol and propranolol
Ralph Howe
pp 398 - 403; DOI:
10.1021/jm00297a015
PDF
New class of sympathetic .beta.-receptor blocking agents. 3,4-Dihydro-3-hydroxy-1,5-benzoxazocines
Berkeley Basil, E. C. J. Coffee, D. L. Gell, Donald R. Maxwell, D. J. Sheffield, and Kenneth R. H. Wooldridge
pp 403 - 406; DOI:
10.1021/jm00297a016
PDF
Synthesis of 6-(N-alkyl-N-arylamino)pyrimidines as potential antimetabolites
Paul L. Warner and Thomas J. Bardos
pp 407 - 410; DOI:
10.1021/jm00297a017
PDF
Preparation and activity of the 4'-thio-derivatives of some 6-substituted purines nucleosides
Miroslav Bobek, Roy L. Whistler, and Alexander Bloch
pp 411 - 413; DOI:
10.1021/jm00297a018
PDF
Experimental antileukemic agents. Preparation and structure-activity study of S-tritylcysteine and related compounds
Kwang-Yuen Zee-Cheng and Chia-Chung Cheng
pp 414 - 418; DOI:
10.1021/jm00297a019
PDF
Synthesis and pharmacological evaluation of .alpha.-naphthylalkylamines
Silvano Casadio, Gianfranco Pala, Tiberio Bruzzese, Carla Turba, and Ernesta Marazzi-Uberti
pp 418 - 421; DOI:
10.1021/jm00297a020
PDF
Anticancer agents. IV. Antitumor activity of some 1,4- and 1,5-(bisthiosemicarbazones) and of related heterocycles
Vincent C. Barry, Michael L. Conalty, Joan E. McCormick, Robert S. McElhinney, Mary R. McInerney, and John F. O'Sullivan
pp 421 - 427; DOI:
10.1021/jm00297a021
PDF
2-Fluoropurine ribonucleosides
John A. Montgomery and Kathleen Hewson
pp 427 - 430; DOI:
10.1021/jm00297a022
PDF
Potential antitumor agents. IV. 4-Substituted 1-formylisoquinoline thiosemicarbazones
Krishna C. Agrawal, Robert J. Cushley, Walter J. McMurray, and Alan C. Sartorelli
pp 431 - 434; DOI:
10.1021/jm00297a023
PDF
Model studies for the reactivation of aged phosphonylated acetylcholinesterase. Use of alkylating agents containing nucleophilic groups
George M. Steinberg, Claire N. Lieske, Roger Boldt, John C. Goan, and Harold E. Podall
pp 435 - 446; DOI:
10.1021/jm00297a024
PDF
Alkylating agents related to 2,2'-biaziridine. III. Stereoisomeric N,N'-dimethylsulfonyl-2,2'-biaziridines
Peter W. Feit and Ole T. Nielsen
pp 447 - 452; DOI:
10.1021/jm00297a025
PDF
Structure-activity relations in adenosine deaminase inhibitors
Howard J. Schaeffer, Roland Norman Johnson, E. Odin, and Corwin Hansch
pp 452 - 455; DOI:
10.1021/jm00297a026
PDF
Irreversible enzyme inhibitors. CLXIX. Inhibition of FUDR [5-fluoro-2'-deoxyuridine] phosphorylase from Walker 256 rat tumor by 6-substituted uracils
Bernard Randall Baker and James L. Kelley
pp 456 - 458; DOI:
10.1021/jm00297a027
PDF
Irreversible enzyme inhibitors. CLXX. Inhibition of FUDR [5-fluoro-2'-deoxyuridine] phosphorylase from Walker 256 rat tumor by 1-substituted uracils
Bernard Randall Baker and James L. Kelley
pp 458 - 461; DOI:
10.1021/jm00297a028
PDF
Irreversible enzyme inhibitors. CLXXI. Inhibition of FUDR [5-fluoro-2'-deoxyuridine] phosphorylase from Walker 256 rat tumor by 5-substituted uracils
Bernard Randall Baker and James L. Kelley
pp 461 - 467; DOI:
10.1021/jm00297a029
PDF
Irreversible enzyme inhibitors. CLXXII. Proteolytic enzymes. XVI. Covalent bonding of the sulfonyl fluoride group to serine outside the active-site of .alpha.-chymotrypsin by exo-type active-site directed irreversible inhibitors
Robert Cardinaud and Bernard Randall Baker
pp 467 - 470; DOI:
10.1021/jm00297a030
PDF
Nucleophilicity of heteroaromatic aldoximes bearing an aminoalkyl side chain. IV
Yacov Ashani and Sasson Cohen
pp 471 - 474; DOI:
10.1021/jm00297a031
PDF
Mechanism of metabolic 3-hydroxylation of benzodiazepines. Fragmentation pattern of 1,4-benzodiazepin-2-ones under electron impact
Wolfgang Sadee
pp 475 - 479; DOI:
10.1021/jm00297a032
PDF
Agents acting on the central nervous system. XII. 3-Tert-aminopropiophenones as central muscle relaxants and diuretics
H. P. S. Chawla, B. C. Gautam, R. S. Kapil, Nitya Anand, G. K. Patnaik, Man M. Vohra, and O. P. Shrivastava
pp 480 - 488; DOI:
10.1021/jm00297a033
PDF
1,2,3,4,5,6-Hexahydro-6-phenyl-2,6-methano-3-benzazocines. II
Naokata Yokoyama, Fred B. Block, and Frank H. Clarke
pp 488 - 492; DOI:
10.1021/jm00297a034
PDF
Linear free energy relations in the alkaline hydrolysis of substituted benzoylcholine esters
James J. Zimmerman and Jere E. Goyan
pp 492 - 497; DOI:
10.1021/jm00297a035
PDF
Metabolism of pyrovalerone hydrochloride
Werner Michaelis, Jeff H. Russel, and Othmar Schindler
pp 497 - 503; DOI:
10.1021/jm00297a036
PDF
Structure-dependent inhibition by synthetic fibrinolytic anions of collagen-induced aggregation of human platelets
Detlev Thilo and Kurt N. Von Kaulla
pp 503 - 510; DOI:
10.1021/jm00297a037
PDF
Influence of lipophilic character on the antibacterial activity of cephalosporins and penicillins
Gian L. Biagi, Maria C. Guerra, Anna M. Barbaro, and Maria F. Gamba
pp 511 - 516; DOI:
10.1021/jm00297a038
PDF
Agents acting on the central nervous system. XIII. 2,3,4,4a,5,6-Hexahydro-1(H)-pyrazino[1,2-a]quinolines. A new class of hypotensive agents
V. Aruna Rao, Padam C. Jain, Nitya Anand, R. C. Srimal, and Prithvi R. Dua
pp 516 - 522; DOI:
10.1021/jm00297a039
PDF
Benzo[g]quinolines. II. Novel synthesis and pharmacological evaluation of cis-1-alkyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolines
William F. Michne and Noel F. Albertson
pp 522 - 525; DOI:
10.1021/jm00297a040
PDF
Novel analgetics and molecular rearrangements in the morphine-thebaine group. XVIII. 3-Deoxy-6,14-endo-etheno-6,7,8,14-tetrahydrooripavines
John William Lewis and Michael J. Readhead
pp 525 - 527; DOI:
10.1021/jm00297a041
PDF
Central nervous system stimulants of the xanthone series
Paolo Da Re, Laura Sagramora, Vittorio Mancini, P. Valenti, and Lorenzo Cima
pp 527 - 531; DOI:
10.1021/jm00297a042
PDF
Thia steroids. III. Derivatives of 2-thia-A-nor-5.alpha.-androstan-17.beta.-ol as probes of steroid-receptor interactions
Manfred E. Wolff, Galal Zanati, G. Shanmugasundarum, Sharad Gupte, and Gunhild Aadahl
pp 531 - 534; DOI:
10.1021/jm00297a043
PDF
Potential naphthoquinone antimalarials. 2-Acylhydrazino-1,4-naphthoquinonones
Kenneth H. Dudley and H. Wayne Miller
pp 535 - 537; DOI:
10.1021/jm00297a044
PDF
Antimalarials. II. Quinolinemethanols with decreased phototoxicity
Edward R. Atkinson and Anthony J. Puttick
pp 537 - 541; DOI:
10.1021/jm00297a045
PDF
Antimalarials. Quinolinemethanol derivatives
Tara Singh and John H. Biel
pp 541 - 541; DOI:
10.1021/jm00297a046
PDF
Antimalarial substances. XXII. Synthetic schistosomicides. XV. Antimalarial and antischistosomal effects of .alpha.,.alpha.,.alpha.,.alpha.',.alpha.',.alpha.'-hexachloroxylene derivatives and related halogenated hydrocarbons
Edward F. Elslager, Marland P. Hutt, and Leslie M. Werbel
pp 542 - 544; DOI:
10.1021/jm00297a047
PDF
Coumarin derivatives as coronary vasodilators
Dilbagh S. Bariana
pp 544 - 546; DOI:
10.1021/jm00297a048
PDF
Antimalarials. Antagonists of pantothenic acid
Raj K. Razdan, Catherine M. Reinsel, and Barbara A. Zitko
pp 546 - 549; DOI:
10.1021/jm00297a049
PDF
Synthesis and microbiological properties of some substituted derivatives of 3-amino-3,4-dihydrocarbostyril
Alvie L. Davis, James W. Hughes, Robert L. Hance, Vicki L. Gault, and Tommy J. McCord
pp 549 - 550; DOI:
10.1021/jm00297a050
PDF
Antiprotozoal quinones. IV. 2-Amino-1,4-naphthoquinone imines as potential antimalarials
Frank J. Bullock, John F. Tweedie, Donna D. McRitchie, and Margaret A. Tucker
pp 550 - 552; DOI:
10.1021/jm00297a051
PDF
Substituted N-phenylanthranilic acid hydrazides as potential antimalarial and antimicrobial agents
N. H. Berner, Rajendra S. Varma, and David W. Boykin
pp 552 - 554; DOI:
10.1021/jm00297a052
PDF
1-Adamantanecarboxylic acid amide of 4-aminoantipyrine
Remo Spano, G. Linari, and R. Marri
pp 554 - 554; DOI:
10.1021/jm00297a053
PDF
2-(Substituted amino)quinolizinium bromides. A new class of anthelmintic agents
Robert J. Alaimo, Christopher J. Hatton, and Michael K. Eckman
pp 554 - 556; DOI:
10.1021/jm00297a054
PDF
Hypoglycemic activity of 1-alkenyl- and 1-alkenoyl-3-arylsulfonylureas
Gianfranco Pala, Antonio Mantegani, Amedeo Omodei-Sale, and Germano Coppi
pp 556 - 557; DOI:
10.1021/jm00297a055
PDF
New class of ultralong-acting local anesthetics
James F. Stubbins, Seymour Ehrenpreis, T. H. Lynes, and M. Bigo-Gullino
pp 558 - 559; DOI:
10.1021/jm00297a056
PDF
Radioopaque contrast media. XVIII. Derivatives of 2-(3-amino-2,4,6-triiodophenyl)alkanoic acids
Ernst Felder, Davide Pitre, Luciano Fumagalli, and Enrico Lorenzotti
pp 559 - 561; DOI:
10.1021/jm00297a057
PDF
Chlorosulfonation of 17.beta.-acetoxy-3-methoxyestra-1,3,5(10)-triene
Arthur H. Goldkamp
pp 561 - 563; DOI:
10.1021/jm00297a058
PDF
Thia steroids. II. 2-Thia-A-nor-5.alpha.-pregnan-20-one
Manfred E. Wolff and Galal Zanati
pp 563 - 563; DOI:
10.1021/jm00297a059
PDF
Pyrolysis of 16-methylene 17-oxygenated-20-keto steroids. IV. Synthesis of 3-hydroxy-1,3,5(10)-estratrienol[17,16-c]-2'-methylfuran
Thomas L. Popper, Olga Gnoj, F. E. Carlon, and Merl Steinberg
pp 564 - 565; DOI:
10.1021/jm00297a060
PDF
N-substituted 2,2'-diphenamic acids and diphenimides. I
Carol A. Cole, Hsi-Lung Pan, Moses J. Namkung, and T. Lloyd Fletcher
pp 565 - 567; DOI:
10.1021/jm00297a061
PDF
Derivatives of fluorene. XXXII. Diphenimides. 2. Some ring substituted N-2-fluorenyl-2',2"-diphenamic acids and diphenimides
Hsi-Lung Pan and T. Lloyd Fletcher
pp 567 - 568; DOI:
10.1021/jm00297a062
PDF
Synthesis of potential anticancer agents. 5,12-Naphthacene-quinones
Jacob Finkelstein and John A. Romano
pp 568 - 570; DOI:
10.1021/jm00297a063
PDF
Reduction of 1-(4-dimethylaminobenzylidene)indene
Carl T. Bahner, David H. Brotherton, Thomas Harmon, and B. L. Stump
pp 570 - 571; DOI:
10.1021/jm00297a064
PDF
Synthesis of additional arylhydroxamic acids which inhibit nucleic acid biosynthesis in vitro
Glen R. Gale, John B. Hynes, and Alayne B. Smith
pp 571 - 574; DOI:
10.1021/jm00297a065
PDF
Glycylureas and quaternary salts
Price Truitt and J. T. Witkowski
pp 574 - 574; DOI:
10.1021/jm00297a066
PDF
Antitumor activity of some azine and hydrazone derivatives of 1,4-dimethoxy-2-butanone
William J. Haggerty and Chia-Chung Cheng
pp 574 - 575; DOI:
10.1021/jm00297a067
PDF
.beta.-Alanyl thio esters
Gil Clifton and Charles G. Skinner
pp 575 - 577; DOI:
10.1021/jm00297a068
PDF
Metal complexes of 1-substituted 3-hydroxyureas
Robert E. Harmon, James C. Dabrowiak, Donald John Brown, Surendra Kumar Gupta, Michael Herbert, and Dakshinamurthy Chitharanjan
pp 577 - 579; DOI:
10.1021/jm00297a069
PDF
Potential antineoplastics. III. Series of 1-thiocarbamoyl-3-methyl-4-arylazo-5-methyl(or phenyl)pyrazoles
Hari G. Garg and Ram Ashrey Sharma
pp 579 - 581; DOI:
10.1021/jm00297a070
PDF
Synthesis of mono-, di-, and trimethoxy derivatives of N,N-bis(2-chloroethyl)aniline and related compounds as antitumor agents
A. H. Sommers, Ursula Biermacher, Sandra B. Brehm, and James H. Short
pp 581 - 583; DOI:
10.1021/jm00297a071
PDF
Benzylidene hydrazides as potential anticancer agents
David W. Boykin and Rajendra S. Varma
pp 583 - 584; DOI:
10.1021/jm00297a072
PDF
Substituted [p-(p-ethoxyphenyl)anilino]acetamides
Giovanni Brancaccio, G. Lettieri, Angelo Larizza, Rene Viterbo, and G. C. Perri
pp 584 - 584; DOI:
10.1021/jm00297a073
PDF
Substituted chroman-6-ylureas and thioureas
G. Lettieri, Giovanni Brancaccio, Angelo Larizza, and Rene Viterbo
pp 584 - 585; DOI:
10.1021/jm00297a074
PDF
The Biochemistry of Viruses
Alfred Burger
pp 586 - 586; DOI:
10.1021/jm00297a900
PDF
Proceedings of the Institute on Drug Literature Evaluation
Maxwell Gordon
pp 586 - 586; DOI:
10.1021/jm00297a901
PDF
The Chemistry and Biochemistry of Steroids
Manfred E. Wolff
pp 586 - 586; DOI:
10.1021/jm00297a902
PDF

Issue 4


Synthetic schistosomicides. XVII. N-(Benzylidene and cinnamylidene)-N'-[2-(diethylamino)ethyl]-1,4-naphthalenediamines and related Schiff bases
Edward F. Elslager, Josephine Battaglia, Annette A. Phillips, and Leslie M. Werbel
pp 587 - 592; DOI:
10.1021/jm00298a001
PDF
Synthetic schistosomicides. XVIII. N-(4-[[2-(Diethylamino)ethyl]amino]-1-naphthyl)amides, N-[5,6,7,8-tetrahydro-4-[(3-piperidinopropyl)amino]-1-naphthyl]amides, and related amide and urea derivatives
Leslie M. Werbel, Josephine Battaglia, Edward F. Elslager, and Carl Youngstrom
pp 592 - 598; DOI:
10.1021/jm00298a002
PDF
Synthesis and schistosomicidal activity of 6-chloro-5-[[2-(diethylamino)ethyl]amino]-8-quinolinemethanol
Denis M. Bailey, Sydney Archer, David Wood, David Rosi, and Allen Yarinsky
pp 598 - 601; DOI:
10.1021/jm00298a003
PDF
Coenzyme Q. CXXII. Identification and ubiquinone-8 biosynthesized by Plasmodium knowlesi, P. cynomolgi, and P. berghei
Frederick S. Skelton, P. J. Rietz, and Karl Folkers
pp 602 - 606; DOI:
10.1021/jm00298a004
PDF
Acyloxymethyl esters of ampicillin
Wolf Von Daehne, E. Frederiksen, E. Gundersen, F. Lund, P. Moerch, Hans J. Petersen, Knud Roholt, L. Tybring, and Wagn O. Godtfredsen
pp 607 - 612; DOI:
10.1021/jm00298a005
PDF
Isoquinolines. 1. 3-Amino- and 3-fluoroisoquinoline derivatives as potential antimalarials
John L. Neumeyer and Klaus K. Weinhardt
pp 613 - 616; DOI:
10.1021/jm00298a006
PDF
Lincomycin. XI. Synthesis and structure of clindamycin, a potent antibacterial agent
Robert D. Birkenmeyer and Fred Kagan
pp 616 - 619; DOI:
10.1021/jm00298a007
PDF
Antiviral phenoxathiins and their analogs. Study of the structure-activity relations for antiviral activity and the replacement ability in poliovirus type III dependent variants
Charles J. Paget, Earleen M. Dennis, Janet Nelson, and Donald C. DeLong
pp 620 - 623; DOI:
10.1021/jm00298a008
PDF
Structure-activity correlations for the central nervous system depressant 2-imidazolidinones
Eric J. Lien, Mehdi Hussain, and Michael P. Golden
pp 623 - 626; DOI:
10.1021/jm00298a009
PDF
Stereochemical studies on medicinal agents. VIII. Absolute stereochemistries of isomethadol isomers
Philip S Portoghese and David Allen Williams
pp 626 - 630; DOI:
10.1021/jm00298a010
PDF
Homologs of benzomorphan derivatives. 1
Mikio Takeda and Hiroshi Kugita
pp 630 - 634; DOI:
10.1021/jm00298a011
PDF
Preparation of substituted naphthylcyclohexane derivatives and related compounds
Humberto Carpio, Wendell H. Rooks, and Pierre Crabbe
pp 634 - 637; DOI:
10.1021/jm00298a012
PDF
Nitrofuryl heterocyclics. 1
M. D. Closier and Peter J. Islip
pp 638 - 640; DOI:
10.1021/jm00298a013
PDF
Synthesis and pharmacology of N-cyano-(.beta.-arylethyl)amines
Edward E. Smissman, Alexandros C. Makriyannis, and Edward J. Walaszek
pp 640 - 644; DOI:
10.1021/jm00298a014
PDF
Piperidine derivatives. 1
Michio Nakanishi, Chiaki Tashiro, Tomohiko Munakata, Kazuhiko Araki, Tatsumi Tsumagari, and Hiroshi Imamura
pp 644 - 648; DOI:
10.1021/jm00298a015
PDF
Synthesis and pharmacological activity of new basic carbamates
Georges Tsatsas, Aspasia Papadakis-Valirakis, Wilbur M. Benson, and Samuel A. Ferguson
pp 648 - 651; DOI:
10.1021/jm00298a016
PDF
Acetylene compounds of potential pharmacological value. XIV. N-(tert-aminoalkynyl)-substituted succinimides and maleimides. Class of central anticholinergic agents
Bo Karlen, Bjorn Lindeke, Sune Lindgren, Karl G. Svensson, Richard Dahlbom, Donald J. Jenden, and John E. Giering
pp 651 - 657; DOI:
10.1021/jm00298a017
PDF
Modified cardenolides. V. Replacement of the C-17 lactone substituent by alkylating groups
Manfred E. Wolff, Hong-Hsi Chang, and Winston Ho
pp 657 - 663; DOI:
10.1021/jm00298a018
PDF
Basic ethers of 1-(p-hydroxyphenyl)-2-phenyl-1,2,3,4-tetrahydroquinoline and 1-(p-hydroxyphenyl)-2-phenylindole. Antifertility agents
Malcolm Rice Bell, Andrew W. Zalay, Rudolf Oesterlin, Philip Schane, and Gordon O. Potts
pp 664 - 668; DOI:
10.1021/jm00298a019
PDF
Synthesis and antiarrhythmic activity of naphthylalkylamines
Gianfranco Pala, Arturo Donetti, Carla Turba, and Silvano Casadio
pp 668 - 671; DOI:
10.1021/jm00298a020
PDF
4-Alkyl-5-aryl-4H-1,2,4-triazole-3-thiols as hypoglycemic agents
M. Y. Mhasalkar, Madhusudan H. Shah, S. T. Nikam, Kodaganallur G. Anantanarayanan, and Chimanlal V. Deliwala
pp 672 - 674; DOI:
10.1021/jm00298a021
PDF
Saligenin analogs of sympathomimetic catechol amines
David T. Collin, David Hartley, David Jack, Lawrence H. C. Lunts, J. C. Press, Alexander C. Ritchie, and Paul Toon
pp 674 - 680; DOI:
10.1021/jm00298a022
PDF
Inhibition of serotonin[3H] uptake by the mouse spleen. Structure-activity study
Robert A. Lahti, Patricia A. Platz, and Barbara J. McAllister
pp 681 - 683; DOI:
10.1021/jm00298a023
PDF
Derivatives of 3,4-dihydro-1(2H)-naphthalenone as .beta.-adrenergic blocking agents. 1. Bunolol and related analogs
Charles F. Schwender, Sheldon Farber, Carol Blaum, and John Shavel
pp 684 - 688; DOI:
10.1021/jm00298a024
PDF
Ionization of histamine, N-acetylhistamine, and their iodinated derivatives
T. B. Paiva, Mineko Tominaga, and Antonio C. M. Paiva
pp 689 - 692; DOI:
10.1021/jm00298a025
PDF
Potential coenzyme inhibitors. IV. 3-Acetyl substituted pyridine and dihydropyridine derivatives
Andrew C. Lovesey
pp 693 - 696; DOI:
10.1021/jm00298a026
PDF
Neuraminidase inhibition and viral chemotherapy
Theodore H. Haskell, Floyd E. Peterson, Donald Watson, Nike R. Plessas, and Townley Culbertson
pp 697 - 704; DOI:
10.1021/jm00298a027
PDF
Synthesis and pharmacological evaluation of some pyridylmethyl substituted ethylenediamines
Seiji Miyano, Akiko Abe, Yoshitoshi Kase, Tomokazu Yuizono, Kuniomi Tachibana, Takeshi Miyata, and Go Kito
pp 704 - 708; DOI:
10.1021/jm00298a028
PDF
Synthesis of 5-mercaptouridine
Gabor L. Szekeres and Thomas J. Bardos
pp 708 - 712; DOI:
10.1021/jm00298a029
PDF
Novel polycyclic heterocycles. Derivatives of 5,11-dihydrodibenz[b,e][1,4]oxazepine and 5,11-dihydrodibenzo[b,e][1,4]thiazepine
Harry L. Yale, Bernard Beer, Jelka Pluscec, and Erwin R. Spitzmiller
pp 713 - 722; DOI:
10.1021/jm00298a030
PDF
Synthesis and hypocholesterolemic activity of alkylidenedithio bisphenols
Martin B. Neuworth, Rohert J. Laufer, James W. Barnhart, J. A. Sefranka, and D. D. McIntosh
pp 722 - 725; DOI:
10.1021/jm00298a031
PDF
Synthesis and antiinflammatory activity of some aryltetrazolylalkanoic acids
Robert T. Buckler, Shin Hayao, O. J. Lorenzetti, Lawrence F. Sancilio, Harold E. Hartzler, and Wallace G. Strycker
pp 725 - 729; DOI:
10.1021/jm00298a032
PDF
Synthesis and screening for antideperessant activity of some aminoindanooxazolines, aminoindanooxazines, and aminoacenaphthoxazolines
Donald L. Trepanier, H. Eldridge Faith, and John N. Eble
pp 729 - 733; DOI:
10.1021/jm00298a033
PDF
Chemotherapeutic nitroheterocycles. 1. Substituted 2-(5-nitro-2-furyl)pyrimidines
Rudolf Albrecht, Klaus Gutsche, Hans J. Kessler, and Eberhard Schroeder
pp 733 - 735; DOI:
10.1021/jm00298a034
PDF
Chemotherapeutic nitroheterocycles. 2. 2-(5-Nitro-2-furyl)pyrimidines with basic substituents
Rudolf Albrecht, Klaus Gutsche, Hans J. Kessler, and Eberhard Schroeder
pp 736 - 737; DOI:
10.1021/jm00298a035
PDF
Reassignment of the absolute configuration of 3-acetoxyquinuclidine methiodide and the absolute configuration of receptor-bound acetylcholine
Bernard Belleau and Peter Pauling
pp 737 - 738; DOI:
10.1021/jm00298a036
PDF
Synthesis of compounds related to muscimol (pantherine, agarin)
Bernard Loev, James William Wilson, and Marjorie M. Goodman
pp 738 - 741; DOI:
10.1021/jm00298a037
PDF
Benzimidazole-5(6)-alanine and related compounds. I. Synthesis of amino acids as inhibitors of norepinephrine biosynthesis
John D. Milkowski, Francis M. Miller, Eugene M. Johnson, and Nicolas Zenker
pp 741 - 742; DOI:
10.1021/jm00298a038
PDF
Synthesis and structure-activity relations of 1-alkoxyalkyl- and 1-aryloxyalkyl-1,4-benzodiazepin-2-ones
Samuel Lamdan, C. H. Gaozza, S. Sicardi, and J. A. Izquierdo
pp 742 - 744; DOI:
10.1021/jm00298a039
PDF
Angiotensin II analogs. IV. Synthesis and biological evaluation of simplified angiotensins
Eugene C. Jorgensen, Graham C. Windridge, and Thomas Choy Lee
pp 744 - 745; DOI:
10.1021/jm00298a040
PDF
Thyroxine analogs. XIX. 3,5-Dimethyl-3'-isopropyl-DL-thyronine
Eugene C. Jorgensen and Jeremy Wright
pp 745 - 747; DOI:
10.1021/jm00298a041
PDF
Central nervous system activity of ethyl 1-naphthylalkylcarbamates
Arturo Donetti and Ernesta Marazzi-Uberti
pp 747 - 748; DOI:
10.1021/jm00298a042
PDF
Synthesis and endocrine activity of some 3-aza-A-homopregnenes
Arvin P. Shroff
pp 748 - 750; DOI:
10.1021/jm00298a043
PDF
Preparation of 6-acetamino-16-methylene-17.alpha.-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate
G. Teutsch, Elliot L. Shapiro, and Hershel L. Herzog
pp 750 - 751; DOI:
10.1021/jm00298a044
PDF
Ring-D-bridged steroid analogs. VIII. Testosterone analogs
Alan J. Solo, J. N. Kapoor, and Peter Hebborn
pp 751 - 754; DOI:
10.1021/jm00298a045
PDF
Analogs of steroid hormones. IV. 16-Keto steroid derivatives
Richard E. Juday and Bonnie Bukwa
pp 754 - 755; DOI:
10.1021/jm00298a046
PDF
Potential specific inhibitors of the lactose transport system of Escherichia coli
Emrys Wyn Thomas
pp 755 - 756; DOI:
10.1021/jm00298a047
PDF
1-Substituted 3-[(5-nitrofurfurylidene)amino]-2-imidazolidinones
Harry R. Snyder, Frank F. Ebetino, A. J. Siedler, and Jon Andersen
pp 756 - 759; DOI:
10.1021/jm00298a048
PDF
Antimalarial sulfilimines and sulfoximines related to diaminodiphenyl sulfoxide and sulfone
Kenneth K. Andersen, Jnanabrata Bhattacharyya, and Sunil K. Mukhopadhyay
pp 759 - 760; DOI:
10.1021/jm00298a049
PDF
Synthesis and antimalarial activity of 4-aminobenzo[g-1,5]naphthyridines
Ned D. Heindel and Stephen A. Fine
pp 760 - 762; DOI:
10.1021/jm00298a050
PDF
Synthesis and antineoplastic evaluation of some 9-substituted acridines
James Thomas Stewart and David M. Shepherd
pp 762 - 762; DOI:
10.1021/jm00298a051
PDF
Potential antineoplastics. IV. 2-Amino-4-methyl-6-phenyl-5-arylazopyrimidines
Hari G. Garg and Ram Ashrey Sharma
pp 763 - 765; DOI:
10.1021/jm00298a052
PDF
Synthesis of 5-iodo-3-indolylphosphodiesters of 5-fluorodeoxyuridine as possible chromogenic cancer chemotherapeutic agents
Kwan-Chung Tsou, Shohei Aoyagi, and Elizabeth Eshelman Miller
pp 765 - 768; DOI:
10.1021/jm00298a053
PDF
Structure-antitumor activity correlation of some Schiff bases
Ernest M. Hodnett and William J. Dunn
pp 768 - 770; DOI:
10.1021/jm00298a054
PDF
Antineoplastic research. I. Pyrazole and pyrimidine derivatives of dehydrocycloheximide analogs
David M. Piatak, C. C. Yen, and R. V. Kennedy
pp 770 - 771; DOI:
10.1021/jm00298a055
PDF
Halogenated 1-(4-aminobenzylidene)indenes
Carl T. Bahner, David H. Brotherton, Jane Cline, Harold Kinder, and Lydia M. Rives
pp 771 - 773; DOI:
10.1021/jm00298a056
PDF
Synthesis and alkylation of tetrahydrocyclopentapyrazolols
Richard P. Williams, Victor J. Bauer, and Sidney R. Safir
pp 773 - 775; DOI:
10.1021/jm00298a057
PDF
Puromycin analogs. Aminoacyl derivatives of 9-(3'-amino-3'-deoxy-.beta.-D-arabino-furanosyl)adenine
Linda V. Fisher, William W. Lee, and Leon Goodman
pp 775 - 777; DOI:
10.1021/jm00298a058
PDF
Alkylation of 5-substituted tetrazoles
Leland Huff and Ronald A. Henry
pp 777 - 779; DOI:
10.1021/jm00298a059
PDF
Aminoadamantane derivatives as potential insect chemosterilants
James E. Oliver and Jerry B. Stokes
pp 779 - 780; DOI:
10.1021/jm00298a060
PDF
Potential antidiabetics. V. 3,5-Dimethyl-4-arylazo-N1-carbamoyl-, 3-methyl-4-arylazo-5-phenyl-N1-carbamoyl-, and 3,5-dimethyl-4-arylazo-N1-hippurylpyrazoles
Wahid U. Malik, Hari G. Garg, Prem P. Singh, and Veena Arora
pp 780 - 782; DOI:
10.1021/jm00298a061
PDF
Insect chemosterilants. IX. N-(Hydroxymethyl)-N,N',N',N'',N''-pentamethylphosphoric triamide
Paul H. Terry and Alexej B. Borkovec
pp 782 - 783; DOI:
10.1021/jm00298a062
PDF
New thio derivatives of carcinogenic arylamines. IV. 4-Acetamido-3-methylthiodiphenyl
T. Lloyd Fletcher, Carol A. Cole, Hsi-Lung Pan, and Moses J. Namkung
pp 784 - 784; DOI:
10.1021/jm00298a063
PDF
New benzimidazoles
William R. Sullivan
pp 784 - 786; DOI:
10.1021/jm00298a064
PDF
Antitumor activities of some Schiff bases
Ernest M. Hodnett and Paul D. Mooney
pp 786 - 786; DOI:
10.1021/jm00298a065
PDF

Issue 5


The Chemistry of the Isoquinoline Alkaloids
Tetsuji Kametaxi
pp 787 - 787; DOI:
10.1021/jm00298a900
PDF
Advances in Biochemical Psychopharmacology
Alfred Burger
pp 787 - 787; DOI:
10.1021/jm00298a901
PDF
Hormonal Contraception
Manfred E. Wolff
pp 787 - 787; DOI:
10.1021/jm00298a902
PDF
Strcutural Units of Medical and Biological Terms. A Convenient Guide, in English, to the Roots, Stems, Prefixes, Suffixes, and Other Combining Forms which are the Building Blocks of Medical and Related Scientific Words
Alfred Burger
pp 787 - 787; DOI:
10.1021/jm00298a903
PDF
The National Formulary
Alfred Burger
pp 788 - 788; DOI:
10.1021/jm00298a904
PDF
Synthetic Methods of Organic Chemistry
Richard J. Sundberg
pp 788 - 788; DOI:
10.1021/jm00298a905
PDF
Thiamine Diphosphate and Its Catalytic Functions
Alfred Burger
pp 788 - 788; DOI:
10.1021/jm00298a906
PDF
Fondamenti di Chimica Farmaceutica
R. Deghenghi
pp 788 - 788; DOI:
10.1021/jm00298a907
PDF
Synthesis of .gamma.-dimethylaminomethyl-.alpha.-phenylcycloalkyl propionates as potential analgetics
Mathias P. Mertes, Arthur A. Ramsey, Patrick E. Hanna, and Duane D. Miller
pp 789 - 794; DOI:
10.1021/jm00299a001
PDF
Analgetics based on the pyrrolidine ring. V
John F. Cavalla, Ian M. Lockhart, Nigel E. Webb, Claude V. Winder, Myrna Welford, and Agnes Wong
pp 794 - 800; DOI:
10.1021/jm00299a002
PDF
Structure-activity correlations of morphinelike analgetics based on efficiencies following intravenous and intraventricular application
Eberhard Kutter, Albert Herz, Hans J. Teschemacher, and Rainer Hess
pp 801 - 805; DOI:
10.1021/jm00299a003
PDF
Optical isomers of miscellaneous strong analgetics
Everette L. May and Mikio Takeda
pp 805 - 807; DOI:
10.1021/jm00299a004
PDF
Tricyclic norephedrine analogs. Isomeric 9-hydroxy-10-amino-1,2,3,4,4a,9,10,10a-(trans-4a,10a)-octahydrophenanthrenes
Wendel Lane Nelson and Duane D. Miller
pp 807 - 814; DOI:
10.1021/jm00299a005
PDF
Synthesis and hypotensive activity of N-substituted 1-trimethoxybenzyl-3-butenylamines and related compounds
F. J. McCarty, L. J. Lendvay, A. J. Vazakas, W. W. Bennetts, F. P. Palopoli, R. Orzechowski, and S. Goldstein
pp 814 - 819; DOI:
10.1021/jm00299a006
PDF
Synthesis and anorectic activity of some 1-benzylcyclopropylamines
Carl Kaiser, Charles A. Leonard, George C. Heil, Bruce M. Lester, David H. Tedeschi, and Charles L. Zirkle
pp 820 - 826; DOI:
10.1021/jm00299a007
PDF
Pyrrolo[3,2,1-jk][1,4]benzodiazepines and pyrrolo[1,2,3-ef][1,5]benzodiazepines which have central nervous system activity
Jackson B. Hester, Allan D. Rudzik, and William Veldkamp
pp 827 - 835; DOI:
10.1021/jm00299a008
PDF
4-Substituted piperidines. V. Local anesthetic 4-aminoalkoxy-4-arylpiperidines
Bert Hermans, Hugo Verhoeven, and Paul Janssen
pp 835 - 838; DOI:
10.1021/jm00299a009
PDF
Polypeptides. XLVI. Synthesis of a stably labeled, biologically active adrenocorticotropin fragment
Luis Moroder and Klaus Hofmann
pp 839 - 843; DOI:
10.1021/jm00299a010
PDF
Synthesis of pyroglutamylhistidylprolineamide by classical and solid phase methods
George Flouret
pp 843 - 845; DOI:
10.1021/jm00299a011
PDF
N-Aminoalkylpolyglycine. Synthesis, antibacterial activity, and electrochemical behavior as a titrant of living cells
Eleonora Santucci, Marcello Marchetti, Franco Alhaique, Claudio Botre, and Fulvio M. Riccieri
pp 846 - 848; DOI:
10.1021/jm00299a012
PDF
Alkylation of 2-methyl-5-nitroimidazole. Some potent antiprotozoal agents
Max Warren Miller, Harold L. Howes, Robert V. Kasubick, and Arthur R. English
pp 849 - 852; DOI:
10.1021/jm00299a013
PDF
Synthesis of potential antimalarial agents. V. Pyrido[2,3-b]pyrazines
Carroll Temple, Jerry D. Rose, Robert Daryl Elliott, and John A. Montgomery
pp 853 - 857; DOI:
10.1021/jm00299a014
PDF
In vivo hydrolysis of isomeric bis(1,1,1-trichloro-2-propyl)1,2-cyclobutanedicarboxylates
Jorge P. Li, John H. Biel, Donald R. Van Harken, Lorraine T. Harmanos, Clarence W. Dixon, and Harold D. Taylor
pp 858 - 859; DOI:
10.1021/jm00299a015
PDF
Antimalarials. II. 8-Quinolinemethanols
J. Samuel Gillespie, Satya P. Acharya, Richard E. Davis, and B. K. Barman
pp 860 - 864; DOI:
10.1021/jm00299a016
PDF
New synthesis of antimalarials related to 2-bromo-4,5-dimethoxy-N,N-bis(diethylaminoethyl)aniline. Terminal nitrogen modifications
Eugene L. Strogryn
pp 864 - 866; DOI:
10.1021/jm00299a017
PDF
Structural modification of febrifugine. Some methylenedioxy analogs
Ping-Lu Chien and Chia-Chung Cheng
pp 867 - 870; DOI:
10.1021/jm00299a018
PDF
Structure and anticoccidial activity among some 4-hydroxyquinolinecarboxylates
Renat H. Mizzoni and et al.
pp 870 - 878; DOI:
10.1021/jm00299a019
PDF
Anticoccidial activity in 1-[2-(cycloalkyl)- and 2-(cycloalkylmethyl-4-amino-5-pyrimidyl)methyl]pyridinium salts
Renat H. Mizzoni and et al.
pp 878 - 882; DOI:
10.1021/jm00299a020
PDF
Quinazolines. VI. Synthesis of 2,4-diaminoquinazolines from anthranilonitriles
Andre Rosowsky, James L. Marini, Marilyn E. Nadel, and Edward J. Modest
pp 882 - 886; DOI:
10.1021/jm00299a021
PDF
Synthesis and activity of some 3-aryl- and 3-aralkyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamides
Bola V. Shetty, Liborio A. Campanella, Telfer L. Thomas, M. Fedorchuk, T. A. Davidson, L. Michelson, H. Volz, S. E. Zimmerman, E. J. Belair, and A. P. Truant
pp 886 - 895; DOI:
10.1021/jm00299a022
PDF
Aminoalkenylbenzenesulfonamides with hypotensive and histamine-releasing properties
Marion T. Dorsett, J. Martin Grisar, Kenneth R. Hickey, Rudolph L. Pohl, William J. Hudak, and Richard E. Lewis
pp 895 - 900; DOI:
10.1021/jm00299a023
PDF
Comparative effects of piperonyl butoxide and N-(4-pentynyl)phthalimide on mammalian microsomal enzyme functions
Herbert Jaffe and John L. Neumeyer
pp 901 - 903; DOI:
10.1021/jm00299a024
PDF
In vivo hydroxylation of the alkaloid acronine, an experimental antitumor agent
Hugh Richard Sullivan, Ruth E. Billings, John L. Occolowitz, Harold E. Boaz, Frederick J. Marshall, and Robert E. McMahon
pp 904 - 909; DOI:
10.1021/jm00299a025
PDF
Choline acetyltransferase inhibitors. Physicochemical properties in relation to inhibitory activity of styrylpyridine analogs
Richard Charles Allen, Gerald L. Carlson, and C. J. Cavallito
pp 909 - 912; DOI:
10.1021/jm00299a026
PDF
Structure-activity relations in thymidine phosphorylase inhibitors. A correlation using substituent constants and regression analysis
Eugene Coats, W. R. Glave, and Corwin Hansch
pp 913 - 919; DOI:
10.1021/jm00299a027
PDF
Mixed bifunctionality. III. Antitumor activity of sesame oil solutions of simple alkylating derivatives of polynuclear hydrocarbons
Richard M. Peck and Anna P. O'Connell
pp 919 - 922; DOI:
10.1021/jm00299a028
PDF
Electron-donating properties of phenothiazine and related compounds
John E. Bloor, Bruce R. Gilson, R. J. Haas, and Charles L. Zirkle
pp 922 - 925; DOI:
10.1021/jm00299a029
PDF
Bridged bicyclic and polycyclic amino acids. Potent new inhibitors of the fibrinolytic process
Larry J. Loeffler, Susan F. Britcher, and Werner Baumgarten
pp 926 - 935; DOI:
10.1021/jm00299a030
PDF
Potential anticancer agents. III. Schiff bases from benzaldehyde nitrogen mustards and aminophenylthiazoles
J. D. Modi, S. S. Sabnis, and C. V. Deliwala
pp 935 - 941; DOI:
10.1021/jm00299a031
PDF
Synthesis of dideoxyzearalanone and hydroxyl derivatives
David B. R. Johnston, Carol A. Sawicki, Thomas B. Windholz, and A. A. Patchett
pp 941 - 944; DOI:
10.1021/jm00299a032
PDF
Relation between lipophilic character and hemolytic activity of testosterone and testosterone esters
Gian L. Biagi, Maria C. Guerra, and Anna M. Barbaro
pp 944 - 948; DOI:
10.1021/jm00299a033
PDF
Steroidal heterocycles. XIII. 4.alpha.,5-Epoxy-5.alpha.-androst-2-eno[2,3-d]isoxazoles and related compounds
H. C. Neumann, G. O. Potts, W. T. Ryan, and F. W. Stonner
pp 948 - 951; DOI:
10.1021/jm00299a034
PDF
Anabolic 19-nortestosterone bicyclo[2.2.2]octane- and -octenecarboxylates
Richard M. Scribner, R. I. Dorfman, and W. H. Rooks
pp 952 - 956; DOI:
10.1021/jm00299a035
PDF
Role of the benzyl moiety in biochemical and pharmacological processes
Corwin Hansch and Richard Kerley
pp 957 - 964; DOI:
10.1021/jm00299a036
PDF
Use of .sigma.+ in structure-activity correlations
Corwin Hansch
pp 964 - 966; DOI:
10.1021/jm00299a037
PDF
Metal chelate steroid analog. [7-Amino-3-(1,5-dimethylhexyl)dodecahydro-3a,6-dimethyl-1H-benz[e]indene-6-methylamine]bis(ethylenediamine)cobalt(3 +) trichloride
Lorraine G. Donaruma and Patricia U. Flath
pp 966 - 967; DOI:
10.1021/jm00299a038
PDF
Synthesis and myotrophic-androgenic activity of 17.beta.-hydroxy-5.alpha.-androst-8(14)-en-3-one derivatives
Manfred Ernst Wolff and Hong-Hsi Chang
pp 967 - 968; DOI:
10.1021/jm00299a039
PDF
Imidazole derivatives. Histidine decarboxylase inhibitors
Leo R. Swett and Tobias O. Yellin
pp 968 - 970; DOI:
10.1021/jm00299a040
PDF
New .beta.-adrenergic blocking agents. Cyclopropylphenyl derivatives
Jacques R. Boissier, Roger Ratouis, Claude Dumont, Pierre H. Derible, and Jean P. Lavaux
pp 971 - 973; DOI:
10.1021/jm00299a041
PDF
2,3,6-Trimethoxynitrostyrene and its .beta.-phenethylamine
Betty Matsuhiro and Arthur Furst
pp 973 - 973; DOI:
10.1021/jm00299a042
PDF
Synthesis of B/C trans-fused morphine structures. V. Pharmacological summary of trans-morphine derivatives and an improved synthesis of trans-codeine
Hiroshi Kugita, Mikio Takeda, and Hirosumi Inoue
pp 973 - 975; DOI:
10.1021/jm00299a043
PDF
Analeptics. 1-Formimidoylindolines
Yao-Hua Wu, Walter G. Lobeck, and John W. Kissel
pp 975 - 977; DOI:
10.1021/jm00299a044
PDF
Synthesis of some local anesthetics
Pramod K. Srivastava and P. N. Srivastava
pp 977 - 979; DOI:
10.1021/jm00299a045
PDF
Synthesis of some substituted 10-amino-10,11-dihydro-5H-dibenz[b,f]azepines
Bijan Prasun Das, Ronald W. Woodard, Larry K. Whisenant, William F. Winecoff, and David W. Boykin
pp 979 - 981; DOI:
10.1021/jm00299a046
PDF
New class of 1,3-benzoxazinones as potential central nervous system agents
Ned D. Heindel and Lee A. Schaeffer
pp 981 - 983; DOI:
10.1021/jm00299a047
PDF
Substituted oxindoles. III. Synthesis and pharmacology of some substituted oxindoles
John Walker, Roy W. Daisley, and Arnold H. Beckett
pp 983 - 985; DOI:
10.1021/jm00299a048
PDF
Demethylation studies. VII. Unique effect of the N-cyclopropyl group in a new series of inhibitors of oxidative microsomal demethylation
Robert E. McMahon, Hilman W. Culp, and Jack Mills
pp 986 - 987; DOI:
10.1021/jm00299a049
PDF
Pyrazine diuretics. VIII. N-Amidino-3-aminopyrazinecarboxamide 4-oxides
James Holden Jones and Edward J. Cragoe
pp 987 - 989; DOI:
10.1021/jm00299a050
PDF
Modification of recovered dominant lethal mutations induced by heteroaromatic aziridines in stored housefly sperm
J. George Pomonis, David T. North, and Richard G. Zaylskie
pp 989 - 991; DOI:
10.1021/jm00299a051
PDF
Potential antineoplastics. V. Synthesis of ethyl 2,3-dioxobutyrate 2-arylhydrazono-3-thiosemicarbazones
Hari G. Garg and Ram Ashrey Sharma
pp 991 - 992; DOI:
10.1021/jm00299a052
PDF
Quaternary indolylpyridinium salts. Oral hypoglycemic agents
William J. Fanshawe, Victor J. Bauer, Sidney R. Safir, D. A. Blickens, and S. J. Riggi
pp 993 - 995; DOI:
10.1021/jm00299a053
PDF
Folic acid analogs. II. p-{[(2,6-Diamino-8-purinyl)methyl]amino}-benzoyl-L-glutamic acid and related compounds
Louis T. Weinstock, Bernard F. Grabowski, and Chia-Chung Cheng
pp 995 - 997; DOI:
10.1021/jm00299a054
PDF
Sodium tyropanoate, a new oral cholecystographic agent
J. O. Hoppe, J. H. Ackerman, A. A. Larsen, and J. Moss
pp 997 - 999; DOI:
10.1021/jm00299a055
PDF
Isoquinolines. 2. 3-(Dialkylaminoalkylamino)isoquinolines as potential antimalarial drugs
John L. Neumeyer and Klaus K. Weinhardt
pp 999 - 1002; DOI:
10.1021/jm00299a056
PDF
Antimalarial agents. VI. 5-Quinolinemethanols
Ivan C. Popoff and Chandrakant B. Thanawalla
pp 1002 - 1004; DOI:
10.1021/jm00299a057
PDF
Potential antimalarials. V. 2-p-Chlorophenyl-7-quinolinemethanols
Lee C. Washburn, T. G. Barbee, and D. E. Pearson
pp 1004 - 1005; DOI:
10.1021/jm00299a058
PDF
Quinoxaline studies. XVII. Potential antimalarials. Some (RS)-.alpha.-(dialkylaminomethyl)-6-chloro-2-quinoxalinemethanols
Henry R. Moreno and Harry P. Schultz
pp 1005 - 1008; DOI:
10.1021/jm00299a059
PDF
Synthesis and antimicrobial activity of 5,7-dichloroquinoline-8-thiol and its derivatives
Alan O. Fitton and Frank Ridgway
pp 1008 - 1009; DOI:
10.1021/jm00299a060
PDF
Structural modification studies of 3-piperonylsydnone. 2. Synthesis of piperonyl-substituted hydantoin, thiohydantoin, thiazolidinedione, rhodanine, imidazolinone, and related compounds
William H. Burton, William L. Budde, and Chia-Chung Cheng
pp 1009 - 1012; DOI:
10.1021/jm00299a061
PDF
In vivo antiviral effects of benzothiazole derivatives against various influenza A2 strains
Stig Akerfeldt
pp 1012 - 1013; DOI:
10.1021/jm00299a062
PDF
Cycloserine derivatives
Charles H. Stammer, C. Chandrasekharan Kartha, Nishith C. Chaturvedi, and James D. McKinney
pp 1013 - 1015; DOI:
10.1021/jm00299a063
PDF
Nitroheterocyclic antimicrobial agents. II. 5-Nitro-1,3,4-thiadiazole-2-carboxaldehyde derivatives
Goro Asato, Gerald Berkelhammer, and Edward L. Moon
pp 1015 - 1017; DOI:
10.1021/jm00299a064
PDF
Indole derivatives
Frank D. Popp
pp 1017 - 1018; DOI:
10.1021/jm00299a065
PDF
Chemistry of azole derivatives. XII. Possible anticonvulsant thiazolo[3,2-a]benzimidazoles
Jag Megh Singh
pp 1018 - 1018; DOI:
10.1021/jm00299a066
PDF
Reinvestigation of the reaction of monosodium urea with various substituted pyrazinecarboxylate esters
J. William Hanifin, Rosemary Capuzzi, and Elliott Cohen
pp 1018 - 1019; DOI:
10.1021/jm00299a067
PDF
N-Aryl-N-aroylamino acid derivatives
A. Larizza, G. Lettieri, and R. Viterbo
pp 1019 - 1020; DOI:
10.1021/jm00299a068
PDF
Ferrocene studies. V. Potential medicinal agents
Frank D. Popp and E. Bradley Moynahan
pp 1020 - 1021; DOI:
10.1021/jm00299a069
PDF
Bis(.alpha.-lactams) derived from adamantane
Erach R. Talaty and Aubry E. Dupuy
pp 1021 - 1022; DOI:
10.1021/jm00299a070
PDF
Derivatives of 2,5-dimethoxy-4-methylamphetamine (DOM)
Beng-Thong Ho, L. Wayne Tansey, and William M. McIsaac
pp 1022 - 1022; DOI:
10.1021/jm00299a071
PDF
1-Substituted 2,5-dimethylpyrroles
Laird F. Miller and Ronald E. Bambury
pp 1022 - 1023; DOI:
10.1021/jm00299a072
PDF

Issue 6


Newer cardiac glycosides and aglycones
Ko Kuei Chen
pp 1029 - 1034; DOI:
10.1021/jm00300a001
PDF
Supplementary glycosides of digitalis
Ko Kuei Chen
pp 1035 - 1037; DOI:
10.1021/jm00300a002
PDF
Small ring analogs of acetylcholine. Synthesis and absolute configurations of cyclopropane derivatives
Joseph G. Cannon and Paul Douglas Armstrong
pp 1037 - 1039; DOI:
10.1021/jm00300a003
PDF
Aromatic amino acid hydroxylase inhibitors. I. Halogenated phenylalanines
Raymond E. Counsell, P. Desai, Terry Douglas Smith, Peter S. Chan, P. A. Weinhold, V. B. Rethy, and D. Burke
pp 1040 - 1042; DOI:
10.1021/jm00300a004
PDF
Inhibition of adrenal phenethanolamine N-methyltransferase by substituted benzimidazoles
Lewis R. Mandel, Curt Culwell Porter, F. A. Kuehl, N. P. Jensen, S. M. Schmitt, T. B. Windholz, T. R. Beattie, J. A. Carty, B. G. Christensen, and Tsung-Ying Shen
pp 1043 - 1047; DOI:
10.1021/jm00300a005
PDF
Imidazole derivatives. IV. Synthesis and pharmacologic activity of oxygenated derivatives of imidazo[1,2-a]pyridine
Luigi Almirante, Alfonso Mugnaini, Nicola De Toma, Afro Gamba, Walter Murmann, and John Hidalgo
pp 1048 - 1051; DOI:
10.1021/jm00300a006
PDF
Aralkylaminoguanidines and related compounds
John B. Bream, Claude W. Picard, Trevor G. White, and Hans Lauener
pp 1051 - 1057; DOI:
10.1021/jm00300a007
PDF
Synthesis and norepinephrine depleting activity of some metaraminol ethers
Walfred S. Saari, Andrew W. Raab, William H. Staas, M. L. Torchiana, Curt Culwell Porter, and Clement Addison Stone
pp 1057 - 1061; DOI:
10.1021/jm00300a008
PDF
Agonists-antagonists derived from desomorphine and metopon
Lewis J. Sargent and Everette L. May
pp 1061 - 1063; DOI:
10.1021/jm00300a009
PDF
Syntheses of heterocyclic compounds. CCCLXXX. Azamorphinan and related compounds. III. Syntheses of 3-hydroxy-N-substituted-9-azamorphinans
Tetsuji Kametani, Kazuo Kigasawa, Mineharu Hiiragi, Nagatoshi Wagatsuma, Kikuo Wakisaka, Fumio Satoh, and Setsu Saito
pp 1064 - 1067; DOI:
10.1021/jm00300a010
PDF
Potential antiinflammatory agents. Aralkoxyhydrouracils and aralkoxyhydantoins
Leon Simet, D. B. Reisner, Bernard J. Ludwig, F. Duersch, and Frank Milan Berger
pp 1067 - 1071; DOI:
10.1021/jm00300a011
PDF
Aminobenzoic acid diuretics. 1. 4-Halogeno-5-sulfamylmetanilic acid derivatives
Peter W. Feit, Herta Bruun, and Christian K. Nielsen
pp 1071 - 1075; DOI:
10.1021/jm00300a012
PDF
Spasmolytics. II. 3-Tropanyl 2,3-diarylacrylates
Henry C. Caldwell, Joseph A. Finkelstein, Philip P. Goldman, Andrew J. Sivak, Jack Schlosser, Carol Pelikan, and William G. Groves
pp 1076 - 1079; DOI:
10.1021/jm00300a013
PDF
Spasmolytics. III. 3-Tropanyl 2,3-diarylacrylates. Case history of .pi.-.sigma. structure-function correlation
Henry C. Caldwell, Paul N. Craig, and William G. Groves
pp 1079 - 1081; DOI:
10.1021/jm00300a014
PDF
New s-triazine derivatives as depressants for reticuloendothelial hyperfunction induced by bacterial endotoxin
Tsutomu Irikura, Yasuo Abe, Kyuya Okamura, Kyoichi Higo, Akitoshi Maeda, Fumihiko Morinaga, Goki Shirai, and Shinkichi Hatae
pp 1081 - 1089; DOI:
10.1021/jm00300a015
PDF
Synthesis and pharmacological evaluation of .alpha.,.alpha.-disubstituted naphthylacetaldehydes
Gianfranco Pala, Arturo Donetti, Antonio Mantegani, Elda Crescenzi, Bruno Lumachi, and Germano Coppi
pp 1089 - 1092; DOI:
10.1021/jm00300a016
PDF
Synthesis and pharmacological properties of N-derivatives of 5,7,12,13-tetrahydro-6H-dibenz[c,g]azonine
Silvano Casadio, Gianfranco Pala, Antonio Mantegani, Ernesta Marazzi-Uberti, Germano Coppi, and Carla Turba
pp 1092 - 1095; DOI:
10.1021/jm00300a017
PDF
Specific competitive inhibition of L-asparaginyl transfer ribonucleic acid lygase by .beta.-aminoamides
T. O. Yellin and M. R. Harnden
pp 1095 - 1098; DOI:
10.1021/jm00300a018
PDF
Polypeptides. XLVII. Effect of the pyrazole-imidazole replacement on the biological activity of thyrotropin-releasing hormone
Klaus Hofmann and Cyril Y. Bowers
pp 1099 - 1101; DOI:
10.1021/jm00300a019
PDF
Antibacterial activity of nitrobenzofurans
Larry J. Powers and Mathias P. Mertes
pp 1102 - 1105; DOI:
10.1021/jm00300a020
PDF
Analogs of the antimalarial 2-bromo-N,N-bis(diethylaminoethyl)-4,5-dimethoxyaniline. 2-Position variations
Eugene L. Stogryn
pp 1106 - 1109; DOI:
10.1021/jm00300a021
PDF
Antimalarials. 1. Aminoalkylamino derivatives of 2,3-dihydrofuroquinolines
Philip A Cruickshank, Fui Tseng Lee, and A. Lupichuk
pp 1110 - 1114; DOI:
10.1021/jm00300a022
PDF
Chemistry of cephalosporin antibiotics. XX. Synthesis and biological properties of 3-acyloxymethyl-7-[2-(thienyl)acetamido]-3-cephem-4-carboxylic acid and related derivatives
Stjepan Kukolja
pp 1114 - 1117; DOI:
10.1021/jm00300a023
PDF
Carcinostatic activity of thiosemicarbazones of formyl heteroaromatic compounds. VI. 1-Formylisoquinoline derivatives bearing additional ring substituents, with notes on mechanism of action
Frederic A. French, Erwin J. Blanz, Jefferson R. DoAmaral, and Douglas A. French
pp 1117 - 1124; DOI:
10.1021/jm00300a024
PDF
Carcinostatic activity of thiosemicarbazones of formyl heteroaromatic compounds. VII. 2-Formylpyridine derivatives bearing additional ring substituents
Frederic A. French, Erwin J. Blanz, Jefferson R. DoAmaral, and Douglas A. French
pp 1124 - 1130; DOI:
10.1021/jm00300a025
PDF
Irreversible enzyme inhibitors. CLXXIII. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine
Bernard Randall Baker, Nicolaas M. J. Vermeulen, Wallace T. Ashton, and Adrian J. Ryan
pp 1130 - 1140; DOI:
10.1021/jm00300a026
PDF
Irreversible enzyme inhibitors. CLXXIV. Metabolism of 4-[p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)hydrocinnamido]-o-toluenesulfonyl fluoride (NSC-113423), and active-site-directed irreversible inhibitor of dihydrofolic reductase
Bernard Randall Baker, Adrian J. Ryan, and Nicolaas M. J. Vermeulen
pp 1140 - 1142; DOI:
10.1021/jm00300a027
PDF
Irreversible enzyme inhibitors. CLXXV. Irreversible inhibition of purifed dihydrofolic reductase
Bernard Randall Baker and Nicolaas M. J. Vermeulen
pp 1143 - 1148; DOI:
10.1021/jm00300a028
PDF
Irreversible enzyme inhibitors. CLXXVI. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine by ether bridging to a terminal sulfonyl fluoride
Bernard Randall Baker and Wallace T. Ashton
pp 1149 - 1154; DOI:
10.1021/jm00300a029
PDF
Irreversible enzyme inhibitors. CLXXVII. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(phenylalkylphenyl)-s-triazines. II
Bernard Randall Baker and Nicolaas M. J. Vermeulen
pp 1154 - 1160; DOI:
10.1021/jm00300a030
PDF
Irreversible enzyme inhibitors. CLXXVIII. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with a terminal sulfonyl fluoride
Bernard Randall Baker and Wallace T. Ashton
pp 1161 - 1165; DOI:
10.1021/jm00300a031
PDF
Ireversible enzyme inhibitors. CLXXIX. Active-site-directed irreversible enzyme inhibitors of dihydrofolate reductase from 1-(3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with oxyamide bridges to a terminal sulfonyl fluoride
Bernard Randall Baker and Wallace T. Ashton
pp 1165 - 1170; DOI:
10.1021/jm00300a032
PDF
Synthesis and biological activity of some 5-(1-adamantyl)pyrimidines. 1
James P. Jonak, Sigmund F. Zakrzewski, Lawrence H. Mead, and Maire T. Hakala
pp 1170 - 1172; DOI:
10.1021/jm00300a033
PDF
Epoxide formation from (2S,3S)-threitol 1,4-bismethanesulfonate. Preparation and biological activity of (2S,3S)-1,2-epoxy-3,4-butanediol 4-methanesulfonate
Peter W. Feit, Niels Rastrup-Andersen, and Rene Matagne
pp 1173 - 1175; DOI:
10.1021/jm00300a034
PDF
Carbamate ester latentiation of physiologically active amines
Leo G. Abood and Anthony J. Verbiscar
pp 1176 - 1179; DOI:
10.1021/jm00300a035
PDF
Peripheral inhibition of thyroxine by thiohydantoins derived from amino acids
Wilfred W. Westerfeld, Joseph V. Marx, and Dan A. Richert
pp 1179 - 1181; DOI:
10.1021/jm00300a036
PDF
Molecular orbital study of 3,3'-5-trihalothyronine analogs
Lemont B. Kier and James R. Hoyland
pp 1182 - 1184; DOI:
10.1021/jm00300a037
PDF
Quantitative structure-activity models. Conditions for application and statistical interpretation
William P. Purcell, Donna R. Hudson, and George E. Bass
pp 1184 - 1189; DOI:
10.1021/jm00300a038
PDF
Structure-activity correlations for anticonvulsant drugs
Eric J. C. Lien
pp 1189 - 1191; DOI:
10.1021/jm00300a039
PDF
Parabolic relation between drug potency and hydrophobicity
James W. McFarland
pp 1192 - 1196; DOI:
10.1021/jm00300a040
PDF
Mass spectral analysis in the identification of human metabolites of warfarin
William F. Trager, Richard J. Lewis, and William A. Garland
pp 1196 - 1204; DOI:
10.1021/jm00300a041
PDF
Benzo[b]thiophene derivatives. XVI. Sulfur isosteres of melatonin, bufotenine, 5-hydroxytryptophan, and related structures
Ernest Campaigne and Alan Dinner
pp 1205 - 1208; DOI:
10.1021/jm00300a042
PDF
Isothiazolecarboxaldoximes and methylated derivatives as therapeutic agents in poisoning by organophosphorus compounds
H. P. Benschop, A. M. Van Oosten, D. H. J. M. Platenburg, and C. Van Hooidonk
pp 1208 - 1212; DOI:
10.1021/jm00300a043
PDF
Perfluoroalkyl carbonyl compounds. 1. Perfluoroaldehyde and perfluorocarboxylic acid derivatives
Stephen S. Szinai, George Crank, and David R. K. Harding
pp 1212 - 1215; DOI:
10.1021/jm00300a044
PDF
Perfluoroalkyl carbonyl compounds. 2. Derivatives of hexafluoroacetone
Stephen S. Szinai, George Crank, and David R. K. Harding
pp 1215 - 1217; DOI:
10.1021/jm00300a045
PDF
Structure-taste relation of aspartic acid amides
Robert H. Mazur, Arthur H. Goldkamp, Patricia A. James, and James M. Schlatter
pp 1217 - 1221; DOI:
10.1021/jm00300a046
PDF
12-Carboxyeudesma-3,11(13)-diene. Novel sesquiterpenic acid with a narrow antifungal spectrum
Gad Shtacher and Yoel Kashman
pp 1221 - 1223; DOI:
10.1021/jm00300a047
PDF
Acyl derivatives of 5-hydroxy-6,7-benzomorphans. Prodine congeners
Mikio Takeda and Everette L. May
pp 1223 - 1224; DOI:
10.1021/jm00300a048
PDF
Conformational study of .beta.-phenethanolamine receptor sites. IV. Synthesis of erythro- and threo-3-amino-2-phenyl-2-butanols
Edward E. Smissman and Stanley J. Vickers
pp 1224 - 1225; DOI:
10.1021/jm00300a049
PDF
2-Amino-5,6-dihydroxyindan-2-carboxylic acid. A potential hypotensive agent
John William Lewis, John Bodenham Taylor, and Michael Jacklin
pp 1226 - 1227; DOI:
10.1021/jm00300a050
PDF
Synthesis and pharmacology of a series of substituted 2-aminomethylpyrroles
Stephen Raines and Csaba A. Kovacs
pp 1227 - 1228; DOI:
10.1021/jm00300a051
PDF
New group of anorexigenic compounds
Kurt Freter, Manfred Goetz, and James T. Oliver
pp 1228 - 1230; DOI:
10.1021/jm00300a052
PDF
Tranquilizing drugs. Carbamates of 4-(4-hydroxypiperidino)-4'-fluorobutyrophenone and analogs
Jorge P. Li, Robert G. Stein, John H. Biel, Jonas A. Gylys, and S. A. Ridlon
pp 1230 - 1232; DOI:
10.1021/jm00300a053
PDF
Biphenylene derivatives with pharmacophoric side chains
Alfred Burger and Sharon S. Hillery
pp 1232 - 1233; DOI:
10.1021/jm00300a054
PDF
Synthesis of potential antimalarial agents. VI. Preparation of 3-(p-chlorophenyl)-8-{[4-(diethylamino)-1-methylbutyl]amino}pyrido[2,3-b]pyrazine
Carroll Temple, Jerry D. Rose, and John A. Montgomery
pp 1234 - 1235; DOI:
10.1021/jm00300a055
PDF
Hydroxylamine derivatives as potential antimalarial agents. 1. Hydroxamic acids
John B. Hynes
pp 1235 - 1237; DOI:
10.1021/jm00300a056
PDF
Organic fluorine compounds. IV. Synthesis and antifungal properties of 2-fluoro fatty acid amides
Herman Gershon, Raymond L. Rodin, Raulo Parmegiani, and Patricia K. Godfrey
pp 1237 - 1239; DOI:
10.1021/jm00300a057
PDF
Analogs of 1-(4-dimethylaminobenzylidene)indene. Modifications of the amino group
Carl T. Bahner, David H. Brotherton, Mary K. Brotherton, Harry Harmon, Norma H. Bingham, Lydia M. Rivers, and Stuart L. Watson
pp 1240 - 1242; DOI:
10.1021/jm00300a058
PDF
5'-Diazogriseofulvin
Howard Newman, Thomas L. Fields, and Robert B. Angier
pp 1242 - 1243; DOI:
10.1021/jm00300a059
PDF
Steroids and related natural products. 63. 17.beta.-Acetoxy-4-oxa-2-androstene
George R. Pettit and Tirumalai R. Kasturi
pp 1244 - 1245; DOI:
10.1021/jm00300a060
PDF
Hypocholesteremic agents. 2. Cyclohexane and indan derivatives
Frank J. Villani and Claire A. Ellis
pp 1245 - 1246; DOI:
10.1021/jm00300a061
PDF
1-Dodecylpyridinium dodecyl sulfate
Gunther S Fonken and Forrest A. MacKellar
pp 1246 - 1246; DOI:
10.1021/jm00300a062
PDF
SH analog of the estrogen hexestrol
Lars Terenius
pp 1246 - 1247; DOI:
10.1021/jm00300a063
PDF
Compounds related to insect juvenile hormone. V. Derivatives of citronellol and citronellylamine
Philip E. Sonnet, Meyer Schwarz, and Nobel Wakabayashi
pp 1247 - 1248; DOI:
10.1021/jm00300a064
PDF
Synthesis of new urethans. p-Ethylsulfonyl- and p-dimethylsulfamoylcarbanilic acid esters
N. Sharghi, Iradj Lalezari, Gh. Niloofari, and F. Ghabgharan
pp 1248 - 1248; DOI:
10.1021/jm00300a065
PDF
Synthesis of 5,7-dimethoxyindole
P. J. Mulligan and S. La Berge
pp 1248 - 1249; DOI:
10.1021/jm00300a066
PDF
Dithienylpiperidylthenilates
Robert D. Schuetz and George P. Nilles
pp 1249 - 1249; DOI:
10.1021/jm00300a067
PDF
Acetylenics. 1. Aromatic amines containing the acetylenic triple bond
David Z. Simon, Romano L. Salvador, and Gaston Champagne
pp 1249 - 1250; DOI:
10.1021/jm00300a068
PDF
Antifungal activity and geometric isomerism. Anilides of o-coumaric acid
Alex Gringauz
pp 1250 - 1250; DOI:
10.1021/jm00300a069
PDF
Potential antidiabetics. VI. 3-Methyl-4-arylhydrazono-2-isoxazolin-5-ones and 3-methyl-4-arylazo-5-(methyl phenyl)isoxazoles
Hari G. Garg and Prem Pal Singh
pp 1250 - 1251; DOI:
10.1021/jm00300a070
PDF
Pyrolysis of 1-adamantyl azidomethyl ketone
Leo H. Sternbach and Robert Y. Ning
pp 1251 - 1252; DOI:
10.1021/jm00300a071
PDF
Book Reviews

pp 1252 - 1253; DOI:
10.1021/jm00300a600
PDF
Additions and Corrections - β-Adrenergic Blocking Agents. V. 1-Amino-3-(substituted phenoxy)-2-propanols.
A. F. Crowther, D. J. Gilman, B. J .McLoughlin, L. H. Smith, R. W. Turner, and T. M. Wood
pp 1253 - 1253; DOI:
10.1021/jm00300a601
PDF
Additions and Corrections - Hypotensive Agents. (+)- and (-)-2-Methoxy-2-(3-methoxyphenyl)ethyl-amine and Related Compounds.
R. Howe, E. H .P. Young, and A. D. Ainley
pp 1253 - 1253; DOI:
10.1021/jm00300a602
PDF
Additions and Corrections - Irreversible Enzyme Inhibitors. CLXVIII.
B. R .Baker, N. M. Vermeulen, and A. J .Ryan
pp 1253 - 1253; DOI:
10.1021/jm00300a603
PDF
Additions and Corrections - Coumarin Derivatives as Coronary Vasodilators.
D. S. Bariana
pp 1253 - 1253; DOI:
10.1021/jm00300a604
PDF